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KIT Ligand 抗体 (Extracellular Domain)

KITLG 适用: 人, 灵长类 WB, EIA, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal hKL12 unconjugated
产品编号 ABIN112014
发货至: 中国
  • 抗原 See all KIT Ligand (KITLG) 抗体
    KIT Ligand (KITLG)
    抗原表位
    • 16
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    • 2
    • 1
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    Extracellular Domain
    适用
    • 98
    • 48
    • 36
    • 4
    • 4
    • 2
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    • 1
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    人, 灵长类
    宿主
    • 99
    • 21
    • 9
    • 1
    小鼠
    克隆类型
    • 100
    • 29
    单克隆
    标记
    • 71
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    This KIT Ligand antibody is un-conjugated
    应用范围
    • 105
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    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This Monoclonal antibody hKL12 is specific for Stem Cell Factor (hSCF). hKL12 is useful for the detection of hSCF in tissues, isolated cells and for studying biological effects of Human Stem Cell Factor in vitro. Antigen distribution on Tissue sections: Bone marrow stromal cells, fibroblasts, and fetal liver cells express SCF. Keratinocytes stain positive.
    交叉反应 (详细)
    Species reactivity (expected):Primates.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography
    免疫原
    Recombinant Human stem cell factor. Remarks: Recombinant Human SFC is an 18.4 kDa polypeptide containing 165 amino acid residues, corresponding to the sequence of the soluble form of SCF. The antigen is a 248 residue protein. The full-length transcript of the corresponding gene product includes a 25-amino acid secretory leader, a 189-amino acid extracellular domain, a 23-amino acid transmembrane region, and a 36-amino acid cytoplasmic tail. The epitope has not been further characterized.
    克隆位点
    HKL12
    亚型
    IgG1
    Top Product
    Discover our top product KITLG Primary Antibody
  • 应用备注
    ELISA (0.15 μg/mL). Has been described to work in Wetsern blots and Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore by adding 0.5 mL distilled water.
    浓度
    0.4 mg/mL
    缓冲液
    PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C.
  • 抗原
    KIT Ligand (KITLG)
    别名
    KITLG / SCF (KITLG 产品)
    别名
    Xkl-1 antibody, Xsl antibody, Xsl-1 antibody, Xsl-2 antibody, steel antibody, KITLG antibody, SCF antibody, kitl antibody, kl-1 antibody, mgf antibody, scf antibody, FPH2 antibody, KL-1 antibody, Kitl antibody, MGF antibody, SF antibody, SHEP7 antibody, Clo antibody, Con antibody, Gb antibody, Kitlg antibody, Mgf antibody, SLF antibody, Sl antibody, blz antibody, contrasted antibody, 710-712 antibody, CSF antibody, KITL antibody, KIT ligand L homeolog antibody, KIT ligand antibody, kit ligand antibody, kitlg.L antibody, KITLG antibody, kitlg antibody, Kitl antibody, Kitlg antibody
    背景
    SCF is a transmembrane protein expressed as two alternatively spliced isoforms, either 220 or 248 amino acids, the former lacking a peptidase cleavage site. The cleavage site is responsible for the release of the soluble form of the protein from the cell surface. The first 164 or 165 residues of the extracellular domain comprise soluble SCF, which exists in solution as a noncovalently linked homodimer. Alone, SCF is a weakly proliferative stimulus but acts synergistically with numerous cytokines. SCF is important in germ cell developement, and an indispensable facor for mast cell proliferation an differentiation.Synonyms: KITL, Kit ligand, MGF, Mast cell growth factor, Stem cell factor, c-Kit ligand
    基因ID
    4254
    NCBI登录号
    NP_000890
    UniProt
    P21583
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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