CD68 抗体 (Biotin)
(1 reference)Quick Overview for CD68 抗体 (Biotin) (ABIN111831)
抗原
See all CD68 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- CD68 antibody (Cat#BM4000B) recognises a single chain glycoprotein of 110 kDa that is expressed predominantly on the lysomal membrane of myeloid cells. Weak cell surface expression also occurs. The antigen is expressed by the majority of tissue macrophages, and weakly be peripheral blood granulocytes. Studies have shown that the antigen recognised by ED1 is the rat homologue of human CD68.
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- Rat spleen cells
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亚型
- IgG1
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anti-CD68 Molecule (CD68) (AA 312-326), (Middle Region) antibody
CD68 适用: 小鼠, 大鼠 FACS, IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-CD68 Molecule (CD68) (AA 42-155) antibodyCD68 适用: 人 FACS, IHC, WB, ELISA, ICC 宿主: 小鼠 Monoclonal 3F7D3 unconjugated
anti-CD68 Molecule (CD68) antibodyCD68 适用: 人, 小鼠, 猴, 大鼠 FACS, IHC, WB, IF, ISt, StM 宿主: 小鼠 Monoclonal C68-684 unconjugated
anti-CD68 Molecule (CD68) (AA 21-120) antibodyCD68 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), ICC, IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-CD68 Molecule (CD68) (AA 150-301) antibodyCD68 适用: 人 FACS, IHC, ELISA, ISt, StM, Coat 宿主: 小鼠 Monoclonal LAMP4-1830 unconjugated
anti-CD68 Molecule (CD68) antibodyCD68 适用: 人 FACS, IHC, WB, IF, ISt, StM 宿主: 小鼠 Monoclonal rLAMP4-824 unconjugated Recombinant Antibody
anti-CD68 Molecule (CD68) (AA 22-319) antibodyCD68 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-CD68 Molecule (CD68) (AA 150-221) antibodyCD68 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal C68-2709 unconjugated
anti-CD68 Molecule (CD68) antibody (PE)CD68 适用: 人 FACS 宿主: 小鼠 Monoclonal Y1-82A PE
anti-CD68 Molecule (CD68) (AA 341-354), (C-Term) antibodyCD68 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Flow Cytometry: Use 10 mLof neat antibody to label 10^6 cells in 100 μL. (Results maybe enhanced using membrane permeabilisation).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, pH 7.2 with 0.09 % Sodium Azide as preservative and 1 % BSA as stabiliser
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "Low-dose indomethacin after ischemic acute kidney injury prevents downregulation of Oat1/3 and improves renal outcome." in: American journal of physiology. Renal physiology, Vol. 297, Issue 6, pp. F1614-21, (2009) (PubMed).
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: "Low-dose indomethacin after ischemic acute kidney injury prevents downregulation of Oat1/3 and improves renal outcome." in: American journal of physiology. Renal physiology, Vol. 297, Issue 6, pp. F1614-21, (2009) (PubMed).
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- CD68 (CD68 Molecule (CD68))
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别名
- CD68
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背景
- The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells.Synonyms: Gp110, Macrophage marker, Macrosialin
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基因ID
- 287435
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NCBI登录号
- NP_001026808
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UniProt
- Q4FZY1
抗原
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