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ELANE 抗体

ELANE 适用: 人 FACS, EIA, Func 宿主: 小鼠 Monoclonal 39A unconjugated
产品编号 ABIN111823
发货至: 中国
  • 抗原 See all ELANE 抗体
    ELANE (Elastase, Neutrophil Expressed (ELANE))
    适用
    • 86
    • 25
    • 24
    • 4
    • 1
    宿主
    • 67
    • 18
    • 4
    • 1
    小鼠
    克隆类型
    • 62
    • 28
    单克隆
    标记
    • 46
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ELANE antibody is un-conjugated
    应用范围
    • 54
    • 38
    • 27
    • 17
    • 13
    • 10
    • 9
    • 8
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Flow Cytometry (FACS), Enzyme Immunoassay (EIA), Functional Studies (Func)
    特异性
    This antibody is specific for Neutrophil Elastase.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography on Protein G
    免疫原
    Elastase from Human Neutrophils.
    克隆位点
    39A
    亚型
    IgG1
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  • 应用备注
    ELISA. Flow Cytometry. Functional Assays.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS, pH 7.2, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ELANE (Elastase, Neutrophil Expressed (ELANE))
    别名
    Neutrophil Elastase (ELANE 产品)
    别名
    ELA2 antibody, GE antibody, HLE antibody, HNE antibody, NE antibody, PMN-E antibody, SCN1 antibody, Ela2 antibody, F430011M15Rik antibody, ela2 antibody, ELANE antibody, elastase, neutrophil expressed antibody, proteinase 3 antibody, ELANE antibody, Elane antibody, prtn3 antibody
    背景
    Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Elastase is a serine protease which exhibits endopeptidase activity on many proteins, its principal substrate, however, is elastin and it is unique among proteases in its ability to hydrolyse native elastin. It is present in the pancreas, leukocytes and serum. Elastase consists of a single polypeptide chain with a molecular weight of 29.5 kDa. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2A is secreted from the pancreas as a zymogen. In other species, elastase 2A has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues. Elastase 1 is not a pancreatic enzyme: clinical literature that describes human elastase 1 activity in the pancreas is actually referring to elastase 2A.Synonyms: Bone marrow serine protease, ELA2, ELANE, Elastase-2, HLE, Human leukocyte elastase, Medullasin, Neutrophil elastase, PMN elastase
    基因ID
    1991
    NCBI登录号
    NP_001963
    UniProt
    P08246
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