ELANE 抗体
Quick Overview for ELANE 抗体 (ABIN111823)
抗原
See all ELANE 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody is specific for Neutrophil Elastase.
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Elastase from Human Neutrophils.
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亚型
- IgG1
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anti-Elastase, Neutrophil Expressed (ELANE) (AA 30-267) antibody
ELANE 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 140-267) antibodyELANE 适用: 人, 猴 ELISA, WB, IHC, FACS 宿主: 小鼠 Monoclonal 6B6B10 unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 30-247) antibodyELANE 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 140-267) antibodyELANE 适用: 人, 大鼠 ELISA, WB, FACS 宿主: 小鼠 Monoclonal 6B6G6 unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) antibodyELANE 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 30-267) antibodyELANE 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) antibodyELANE 适用: 人 ELISA, IHC, FACS 宿主: 兔 Monoclonal 2H12 unconjugated Recombinant Antibody
anti-Elastase, Neutrophil Expressed (ELANE) antibodyELANE 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 168-267) antibodyELANE 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 4E11 unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 27-265) antibodyELANE 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Flow Cytometry. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS, pH 7.2, 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ELANE (Elastase, Neutrophil Expressed (ELANE))
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别名
- Neutrophil Elastase
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背景
- Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Elastase is a serine protease which exhibits endopeptidase activity on many proteins, its principal substrate, however, is elastin and it is unique among proteases in its ability to hydrolyse native elastin. It is present in the pancreas, leukocytes and serum. Elastase consists of a single polypeptide chain with a molecular weight of 29.5 kDa. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2A is secreted from the pancreas as a zymogen. In other species, elastase 2A has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues. Elastase 1 is not a pancreatic enzyme: clinical literature that describes human elastase 1 activity in the pancreas is actually referring to elastase 2A.Synonyms: Bone marrow serine protease, ELA2, ELANE, Elastase-2, HLE, Human leukocyte elastase, Medullasin, Neutrophil elastase, PMN elastase
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基因ID
- 1991
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NCBI登录号
- NP_001963
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UniProt
- P08246
抗原
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