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CD41, CD61 抗体 (Biotin)

适用: 人 FACS 宿主: 小鼠 Monoclonal M148 Biotin
产品编号 ABIN111385
发货至: 中国
  • 抗原 See all CD41, CD61 抗体
    CD41, CD61 (CD41,CD61)
    适用
    • 12
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 20
    小鼠
    克隆类型
    • 20
    单克隆
    标记
    • 10
    • 4
    • 4
    • 2
    This CD41, CD61 antibody is conjugated to Biotin
    应用范围
    • 16
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    Flow Cytometry (FACS)
    纯化方法
    Protein G chromatography.
    克隆位点
    M148
    亚型
    IgG1
    Top Product
    Discover our top product CD41, CD61 Primary Antibody
  • 应用备注
    Suitable for use in Flow Cytometric applications: 1 g to stain 1.0 x 10^6 cells.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL (OD280 nm)
    缓冲液
    0.01 M PBS, pH 7.2, containing 2.0 mM EDTA and 1.0 % BSA as buffer and 0.09 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    CD41, CD61 (CD41,CD61)
    Abstract
    CD41, CD61 产品
    背景
    Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.Synonyms: CD41, CD61, GP2B, GP3A, GPIIb, GPIIb-IIIa, GPalpha IIb, ITGA2B, ITGAB, ITGB3, Integrin alpha-IIb, Integrin beta-3, Platelet membrane glycoprotein IIb
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