CD41, CD61 抗体 (Biotin)
Quick Overview for CD41, CD61 抗体 (Biotin) (ABIN111385)
抗原
See all CD41, CD61 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein G chromatography.
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亚型
- IgG1
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应用备注
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Suitable for use in Flow Cytometric applications: 1 g to stain 1.0 x 10^6 cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.1 mg/mL (OD280 nm)
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缓冲液
- 0.01 M PBS, pH 7.2, containing 2.0 mM EDTA and 1.0 % BSA as buffer and 0.09 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- CD41, CD61 (CD41,CD61)
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背景
- Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.Synonyms: CD41, CD61, GP2B, GP3A, GPIIb, GPIIb-IIIa, GPalpha IIb, ITGA2B, ITGAB, ITGB3, Integrin alpha-IIb, Integrin beta-3, Platelet membrane glycoprotein IIb
抗原
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