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APOA1 抗体

This 小鼠 单克隆 antibody specifically detects APOA1 in RIA 和 EIA. It exhibits reactivity toward 人.
产品编号 ABIN111352
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for APOA1 抗体 (ABIN111352)

抗原

See all APOA1 抗体
APOA1 (Apolipoprotein A-I (APOA1))

适用

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宿主

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小鼠

克隆类型

  • 120
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单克隆

标记

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This APOA1 antibody is un-conjugated

应用范围

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Radioimmunoassay (RIA), Enzyme Immunoassay (EIA)

克隆位点

1405
  • 特异性

    Recognizes Apolipoprotein A1 (Apo AI). No cross reactivity with Apo A-II or Apo B.Aff. Const.:8 x 10e9

    纯化方法

    Protein A Chromatography.

    免疫原

    Purified Human plasma Apo A-I

    亚型

    IgG1
  • 应用备注

    Suitable for use in Competitive RIA or EIA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    3.47 mg/mL (OD280 nm, E1% = 14)

    缓冲液

    PBS, pH 7.0 containing 0.02 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light. Should it contain a precipitate we recommend microcentrifugation before use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    APOA1 (Apolipoprotein A-I (APOA1))

    别名

    Apolipoprotein A I (APO AI)

    背景

    Apolipoprotein A I promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A I is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77 amino acids, an 18 amino acid signal peptide is removed co-translationally and a 6 amino acid propeptide is cleaved post-translationally. Apolipoprotein A I is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease. The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I. The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.Synonyms: APOA1, Apo-AI, ApoA-I, ApoAI

    基因ID

    335

    NCBI登录号

    NP_000030

    UniProt

    P02647

    途径

    Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
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