WB (1:5000), ICC (1:100-500), Flow Cyt (1:10-100). Other applications have not been tested. The optimal dilutions should be determined by end user.
限制
仅限研究用
状态
Liquid
缓冲液
TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.
储存液
Sodium azide, Thimerosal (Merthiolate)
储存条件
4 °C/-20 °C
储存方法
Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.
有效期
12 months
抗原
TIE1
(tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
别名
Tyrosine-Protein Kinase Receptor TIE1
背景
Tyrosine kinase with immunoglobulin-like and EGF-like domains 1, TIE1 is an angiopoietin receptor which in humans is encoded by the TIE1 gene. 1 The receptor tyrosine kinase Tie1 is expressed in both vascular endothelial cells and immature hematopoietic cells. 2 TIE1 upregulates the cell adhesion molecules (CAMs) VCAM-1, E-selectin, and ICAM-1 through a p38-dependent mechanism. Attachment of monocyte derived immune cells to endothelial cells is also enhanced by TIE1 expression. TIE1 has a proinflammatory effect and may play a role in the endothelial inflammatory diseases such as atherosclerosis. 3