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OCT4 抗体

This anti-OCT4 antibody is a 小鼠 单克隆 antibody detecting OCT4 in WB 和 ICC. Suitable for 小鼠.
产品编号 ABIN1112821
发货至: 中国

Quick Overview for OCT4 抗体 (ABIN1112821)

抗原

See all OCT4 (POU5F1) 抗体
OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

适用

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小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This OCT4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC)

克隆位点

N65
  • 免疫原

    Recombinant OCT-4 protein.

    亚型

    IgG1
  • 应用备注

    WB (1:1000), ICC (1:50). Other applications have not been tested. The optimal dilutions should be determined by end user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

    有效期

    12 months
  • 抗原

    OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

    别名

    Octamer-binding transcription factor 4, OCT-4

    背景

    Oct-4 (octamer-binding transcription factor 4) also known as POU5F1 (POU domain, class 5, transcription factor 1) is a homeodomain transcription factor of the POU family. This protein is critically involved in the self-renewal of undifferentiated embryonic stem cells. As such, it is frequently used as a marker for undifferentiated cells. A critical amount of Oct3/4 is required to sustain stem cell self-renewal, and up- or downregulation induces divergent developmental programs. It has also been showed that Oct3 has a role in cardiac development in the early mouse embryo. Oct-4 expression must be closely regulated, too much or too little will cause differentiation of the cells.

    途径

    Stem Cell Maintenance
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