ICAM1 抗体
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- 抗原 See all ICAM1 抗体
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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适用
- 人, 大鼠, Cow
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ICAM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 纯化方法
- Affinity Chromatography on Protein A
- 免疫原
- Raji Human Burkitt's lymphoma cell line. Genename: ICAM1
- 克隆位点
- MEM-111
- 亚型
- IgG2a
- Top Product
- Discover our top product ICAM1 Primary Antibody
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- 应用备注
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Immunohistochemistry on Paraffin Sections: Recommended Dilution: 10 μg/mLPositive tissue: thymus, RE cellsFlow Cytometry. ELISA. Western blotting (Non-Reducing Conditions). Positive Control: RAJI cell line, K562 leukemia cell line, JY cell line, ActivatedT-lymphocytes.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS, pH ~7.4, 15 mM Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C (addition of a conserving agent is highly recommended) or (in aliquots) at -20 °C.
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LILRA2 activation inhibits dendritic cell differentiation and antigen presentation to T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 12, pp. 8128-36, (2007) (PubMed).
: "Detection of mRNA transcripts of truncated opiate precursor (POMC) in human cartilage." in: Cell biochemistry and function, Vol. 24, Issue 3, pp. 229-35, (2006) (PubMed).
: "Susceptibility of immature and mature Langerhans cell-type dendritic cells to infection and immunomodulation by human cytomegalovirus." in: Journal of virology, Vol. 77, Issue 13, pp. 7563-74, (2003) (PubMed).
: "Colon carcinoma cell glycolipids, integrins, and other glycoproteins mediate adhesion to HUVECs under flow." in: American journal of physiology. Cell physiology, Vol. 284, Issue 4, pp. C977-87, (2003) (PubMed).
: "Eotaxin-2 alters eosinophil integrin function via mitogen-activated protein kinases." in: American journal of respiratory cell and molecular biology, Vol. 26, Issue 6, pp. 645-9, (2002) (PubMed).
: "Molecular mechanisms of improved adhesion and growth of an endothelial cell line cultured on polystyrene implanted with fluorine ions." in: Biomaterials, Vol. 21, Issue 11, pp. 1173-9, (2000) (PubMed).
: "Fluorine ion-implanted polystyrene improves growth and viability of vascular smooth muscle cells in culture." in: Journal of biomedical materials research, Vol. 49, Issue 3, pp. 369-79, (2000) (PubMed).
: "A variety of cytokines and immunologically relevant surface molecules are expressed by normal human skeletal muscle cells under proinflammatory stimuli." in: Clinical and experimental immunology, Vol. 113, Issue 3, pp. 407-14, (1998) (PubMed).
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LILRA2 activation inhibits dendritic cell differentiation and antigen presentation to T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 12, pp. 8128-36, (2007) (PubMed).
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- 抗原
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
- 别名
- CD54 / ICAM1 (ICAM1 产品)
- 物质类
- Viral Protein
- 背景
- ICAM-1 (MW 90 kD) is a member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.Synonyms: ICAM-1, Intercellular adhesion molecule 1, Major Group Rhinovirus Receptor
- 基因ID
- 9606
- UniProt
- P05362
- 途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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