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ICAM1 抗体

ICAM1 适用: 人, 大鼠, Cow WB, FACS, IHC (p), EIA 宿主: 小鼠 Monoclonal MEM-111 unconjugated
产品编号 ABIN111278
发货至: 中国
  • 抗原 See all ICAM1 抗体
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    适用
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    人, 大鼠, Cow
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This ICAM1 antibody is un-conjugated
    应用范围
    • 165
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    纯化方法
    Affinity Chromatography on Protein A
    免疫原
    Raji Human Burkitt's lymphoma cell line. Genename: ICAM1
    克隆位点
    MEM-111
    亚型
    IgG2a
    Top Product
    Discover our top product ICAM1 Primary Antibody
  • 应用备注
    Immunohistochemistry on Paraffin Sections: Recommended Dilution: 10 μg/mLPositive tissue: thymus, RE cellsFlow Cytometry. ELISA. Western blotting (Non-Reducing Conditions). Positive Control: RAJI cell line, K562 leukemia cell line, JY cell line, ActivatedT-lymphocytes.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH ~7.4, 15 mM Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C (addition of a conserving agent is highly recommended) or (in aliquots) at -20 °C.
  • Lee, Sieling, Ochoa, Krutzik, Guo, Hernandez, Rea, Cheng, Colonna, Modlin: "LILRA2 activation inhibits dendritic cell differentiation and antigen presentation to T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 12, pp. 8128-36, (2007) (PubMed).

    Andjelkov, Elvenes, Figenschau, Bjorkoy, Knutsen, Seternes, Johansen: "Detection of mRNA transcripts of truncated opiate precursor (POMC) in human cartilage." in: Cell biochemistry and function, Vol. 24, Issue 3, pp. 229-35, (2006) (PubMed).

    Hertel, Lacaille, Strobl, Mellins, Mocarski: "Susceptibility of immature and mature Langerhans cell-type dendritic cells to infection and immunomodulation by human cytomegalovirus." in: Journal of virology, Vol. 77, Issue 13, pp. 7563-74, (2003) (PubMed).

    Burdick, McCaffery, Kim, Bochner, Konstantopoulos: "Colon carcinoma cell glycolipids, integrins, and other glycoproteins mediate adhesion to HUVECs under flow." in: American journal of physiology. Cell physiology, Vol. 284, Issue 4, pp. C977-87, (2003) (PubMed).

    Tachimoto, Kikuchi, Hudson, Bickel, Hamilton, Bochner: "Eotaxin-2 alters eosinophil integrin function via mitogen-activated protein kinases." in: American journal of respiratory cell and molecular biology, Vol. 26, Issue 6, pp. 645-9, (2002) (PubMed).

    Bacáková, Mares, Lisá, Svorcík: "Molecular mechanisms of improved adhesion and growth of an endothelial cell line cultured on polystyrene implanted with fluorine ions." in: Biomaterials, Vol. 21, Issue 11, pp. 1173-9, (2000) (PubMed).

    Bacáková, Mares, Bottone, Pellicciari, Lisá, Svorcík: "Fluorine ion-implanted polystyrene improves growth and viability of vascular smooth muscle cells in culture." in: Journal of biomedical materials research, Vol. 49, Issue 3, pp. 369-79, (2000) (PubMed).

    Nagaraju, Raben, Merritt, Loeffler, Kirk, Plotz: "A variety of cytokines and immunologically relevant surface molecules are expressed by normal human skeletal muscle cells under proinflammatory stimuli." in: Clinical and experimental immunology, Vol. 113, Issue 3, pp. 407-14, (1998) (PubMed).

  • 抗原
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    别名
    CD54 / ICAM1 (ICAM1 产品)
    物质类
    Viral Protein
    背景
    ICAM-1 (MW 90 kD) is a member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.Synonyms: ICAM-1, Intercellular adhesion molecule 1, Major Group Rhinovirus Receptor
    基因ID
    9606
    UniProt
    P05362
    途径
    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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