C5 抗体
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- 抗原 See all C5 抗体
- C5 (Complement Component 5 (C5))
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适用
- 人, Pig, Cow, 山羊, 灵长类
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This C5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
- 特异性
- HCC 5b.1 (neo) allows detection of C5b-9 complexes via activated C5, especially in different forms of glomerulonephritis. Does not react with native C5! Polypeptide Reacting: Mr 200 000 polypeptide of SDS denaturated complement component C5 and C5b of Mr 185 000, after C5b activation, an Mr 60 000 cleavage product also reacts (weakly). Disorders Specifically Detected: Detection of C5b-9 complexes via activated C5, whereas native C5 reacts with antibody HCC 5.1.
- 交叉反应 （详细）
- Species reactivity (tested):Human, Primates, Bovine, Pig, Goat.
- 纯化方法
- Affinity Chromatography on Protein A
- 免疫原
- Activated Human Complement Component C5
- 克隆位点
- HCC5b-1 (neo)
- 亚型
- IgG1
- Top Product
- Discover our top product C5 Primary Antibody
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anti-Complement Component 5 (C5) (AA 1-18), (N-Term) antibody
C5 适用: 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 5 (C5) (AA 701-755) antibodyC5 适用: 人, 小鼠 WB, ELISA, IF (p), IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 5 (C5) (AA 253-281) antibodyC5 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 5 (C5) (AA 253-281), (N-Term) antibodyC5 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21866 unconjugated
anti-Complement Component 5 (C5) (C-Term) antibodyC5 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 5 (C5) (AA 1-77) antibodyC5 适用: 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 5 (C5) (AA 253-281), (N-Term) antibodyC5 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 5 (C5) (AA 1550-1661) antibodyC5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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ELISA. Immunoblotting (Western blot). Cytological material. Immunohistochemistry on Frozen Sections (1/10). Incubation time: 1h at RT.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 溶解方式
- Restore with 1 mL distilled water.
- 注意事项
- This product is photosensitive and should be protected from light
- 储存条件
- 4 °C
- 储存方法
- Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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- 抗原
- C5 (Complement Component 5 (C5))
- 别名
- Complement C5 (C5 产品)
- 别名
- C5 antibody, LOC565774 antibody, C5a antibody, C5b antibody, CPAMD4 antibody, Hc antibody, RGD1561905 antibody, He antibody, complement C5 antibody, complement component 5 antibody, hemolytic complement antibody, C5 antibody, c5 antibody, Hc antibody
- 背景
- C5 is synthesised in the liver as a single polypeptide chain. Before secretion the molecule is glycosylated and secreted into plasma as a 190 kDa glycoprotein consisting of a disulphide linked alpha-chain (111 kDa) and beta-chain (75 kDa). C5 precursor is first processed by the removal of 4 basic residues, forming two chains, beta and alpha, linked by a disulfide bond. C5 convertase activates C5 by cleaving the alpha chain, releasing C5a anaphylatoxin and generating C5b (beta chain + alpha' chain).Synonyms: CPAMD4, Complement Component 5
- 基因ID
- 727
- NCBI登录号
- NP_001726
- UniProt
- P01031
- 途径
- Complement System, Carbohydrate Homeostasis
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