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C3 抗体

C3 适用: 人, 豚鼠, 兔 WB, IHC (fro), EIA 宿主: 小鼠 Monoclonal H13 unconjugated
产品编号 ABIN111064
发货至: 中国
  • 抗原 See all C3 抗体
    C3 (Complement Component 3 (C3))
    适用
    • 87
    • 54
    • 34
    • 4
    • 4
    • 4
    • 3
    • 2
    人, 豚鼠, 兔
    宿主
    • 68
    • 43
    • 25
    • 8
    • 7
    • 5
    小鼠
    克隆类型
    • 123
    • 32
    单克隆
    标记
    • 65
    • 24
    • 23
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This C3 antibody is un-conjugated
    应用范围
    • 100
    • 49
    • 37
    • 32
    • 32
    • 29
    • 29
    • 27
    • 22
    • 17
    • 13
    • 12
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    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    特异性
    This Monoclonal antibody Clone H 13 recognizes a C3a-determinant (eg C3 alpha-chain) which is present also on native C3. H 13 allows discrimination of ubiquitous or nonspecifically bound native C3 from biologically active C3b fragment, C3b or C are negative with H 13.
    交叉反应 (详细)
    Species reactivity (tested):Human, Guinea Pig and Rabbit.
    纯化方法
    Protein A Chromatography
    免疫原
    Human complement component C3
    克隆位点
    H13
    亚型
    IgG2b
    Top Product
    Discover our top product C3 Primary Antibody
  • 应用备注
    Immunohistochemistry on frozen sections: 1: 10. Western Blot. ELISA. Detection of C3 deposits in tissue, cells, micro-organisms and immune complexes. Itshould be used with positive control anti-C3b (H11/H206). Non-activated, absorbed C3contains the C3a determinant, whereas activated C3 is negative with H 13
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with 1 mL distilled water
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • 抗原
    C3 (Complement Component 3 (C3))
    别名
    Complement C3 (C3 产品)
    别名
    AHUS5 antibody, ARMD9 antibody, ASP antibody, C3a antibody, C3b antibody, CPAMD1 antibody, AI255234 antibody, HSE-MSF antibody, Plp antibody, C3 antibody, C3-1 antibody, sb:cb26 antibody, si:dkey-76b14.4 antibody, wu:fi34b03 antibody, wu:fj86e11 antibody, C3d antibody, asp antibody, cpamd1 antibody, c3 antibody, complement C3 antibody, complement component 3 antibody, complement component c3a, duplicate 1 antibody, complement component 3 L homeolog antibody, complement component C3 antibody, complement C3-like antibody, C3 antibody, c3a.1 antibody, c3.L antibody, LOC443475 antibody, c3 antibody, c3-1 antibody, LOC100060539 antibody
    背景
    The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, CPAMD1, Complement component 3
    基因ID
    718
    NCBI登录号
    NP_000055
    UniProt
    P01024
    途径
    Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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