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TREM1 抗体

TREM1 适用: 人 WB, Func, EIA 宿主: 小鼠 Monoclonal 6B1 unconjugated
产品编号 ABIN1109324
发货至: 中国
  • 抗原 See all TREM1 抗体
    TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))
    适用
    • 63
    • 45
    • 35
    • 16
    • 4
    • 1
    • 1
    • 1
    宿主
    • 73
    • 16
    • 8
    小鼠
    克隆类型
    • 75
    • 21
    单克隆
    标记
    • 45
    • 7
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    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    This TREM1 antibody is un-conjugated
    应用范围
    • 88
    • 49
    • 33
    • 26
    • 15
    • 13
    • 9
    • 9
    • 7
    • 5
    • 4
    • 3
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    • 2
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    • 1
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    Western Blotting (WB), Functional Studies (Func), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes human triggering receptor expressed on myeloid cells 1 (TREM-1). It recognizes both membrane bound and soluble TREM-1. Also, the antibody neutralizes the interaction between TREM-1 and its ligand.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Protein G
    免疫原
    Recombinant TREM-1 - IgG1 fusion protein
    克隆位点
    6B1
    亚型
    IgG1
    Top Product
    Discover our top product TREM1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.1 % bovine serum albumin
    储存条件
    4 °C
    储存方法
    Store at 2 - 8 °C.
  • 抗原
    TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))
    别名
    TREM1 (TREM1 产品)
    别名
    TREM1 antibody, CD354 antibody, TREM-1 antibody, triggering receptor expressed on myeloid cells 1 antibody, TREM1 antibody, Trem1 antibody, LOC100349504 antibody
    背景
    TREM-1 is a transmembrane glycoprotein belonging to a family related to the natural killer cell receptors. TREM-1 is an important activating receptor, of 26 kDa, involved in the innate inflammatory response and in sepsis. TREM-1 is expressed at low levels in the early development of the hematopoietic system and in the promonoistic stage and at high levels on neutrophil granulocytes (PMN), monocytes, and macrophage subsets. The expression of TREM-1 is upregulated by microbial products, that is, by toll-like receptor ligands such as lipoteichoic acid (LTA) of Gram-positive or lipopolysaccharide (LPS) of Gram-negative bacteria. Ligation of TREM-1 is synergistic with TLR agonists on the activation of receptor bearing cells. Platelets express a natural ligand for TREM-1. Receptor ligation activates the full repertoire of effector functions. TREM-1 is also produced in a soluble form (sTREM-1) of 17 kDa which is released in humans after endotoxin exposition or in patients suffering from severe pneumonia or sepsis. sTREM-1 can be measured in biological fluids and may be useful as a diagnostic tool.Synonyms: Triggering receptor expressed on monocytes 1, Triggering receptor expressed on myeloid cells 1
    基因ID
    54210
    NCBI登录号
    NP_061113
    UniProt
    Q9NP99
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