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Siglec H 抗体 (FITC)

This anti-Siglec H antibody is a 大鼠 单克隆 antibody detecting Siglec H in IHC (fro). Suitable for 小鼠.
产品编号 ABIN1109011
发货至: 中国

Quick Overview for Siglec H 抗体 (FITC) (ABIN1109011)

抗原

Siglec H

适用

小鼠

宿主

  • 4
大鼠

克隆类型

  • 4
单克隆

标记

  • 4
This Siglec H antibody is conjugated to FITC

应用范围

  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

440c
  • 交叉反应 (详细)

    Species reactivity (tested):Mouse

    纯化方法

    Protein G

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.02 % sodium azide, 1 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2 - 8 °C.
  • 抗原

    Siglec H

    别名

    Siglec-H

    背景

    Siglec H is unique among Sialic acid-binding Ig-like lectins (Siglecs) proteins because it associates with the adaptor protein DAP12. DAP12 recognize certain viruses and CpG-DNA through TLR9, resulting in secretion of IFN-alpha, IL-12 and proinflammatory chemokines. Together these cytokines and chemokines recruite and activate NK cells and T cells as well as modulating the antigen presenting function of dendritic cells (DC). IPC themselves also function as antigen presenting cells that expand memory T cells and induce Th1 differentiation. Therefore IPC may provide a first line of host defense against viral infections by activating both innate and adaptive responses in vivo.

    UniProt

    Q3Y597
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