Siglec H 抗体
适用: 小鼠
IHC (fro), Func
宿主: 大鼠
Monoclonal
440c
unconjugated
-
- 抗原 See all Siglec H products
- Siglec H
- 适用
- 小鼠
-
宿主
- 大鼠
-
克隆类型
- 单克隆
-
标记
- This Siglec H antibody is un-conjugated
-
应用范围
- Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- 交叉反应 （详细）
- Species reactivity (tested):Mouse
- 纯化方法
- Protein G
- 克隆位点
- 440c
- 亚型
- IgG2b
-
anti-Siglec H (AA 109-309) antibody
适用: 小鼠 WB 宿主: 大鼠 Monoclonal ABM2B55 unconjugated
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 浓度
- 0.1 mg/mL
- 缓冲液
- PBS, 0.1 % bovine serum albumin
- 储存条件
- 4 °C
- 储存方法
- Store at 2 - 8 °C.
-
- 抗原
- Siglec H
- 别名
- Siglec-H (Siglec H 产品)
- 别名
- 6430529G09Rik antibody, Siglec-H antibody, sialic acid binding Ig-like lectin H antibody, Siglech antibody
- 背景
- Siglec H is unique among Sialic acid-binding Ig-like lectins (Siglecs) proteins because it associates with the adaptor protein DAP12. DAP12 recognize certain viruses and CpG-DNA through TLR9, resulting in secretion of IFN-alpha, IL-12 and proinflammatory chemokines. Together these cytokines and chemokines recruite and activate NK cells and T cells as well as modulating the antigen presenting function of dendritic cells (DC). IPC themselves also function as antigen presenting cells that expand memory T cells and induce Th1 differentiation. Therefore IPC may provide a first line of host defense against viral infections by activating both innate and adaptive responses in vivo.
- UniProt
- Q3Y597
-
You are here:
