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PTK7 抗体 (N-Term)

PTK7 适用: 人, 小鼠, 小鸡 WB, EIA, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1108790
发货至: 中国
  • 抗原 See all PTK7 抗体
    PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))
    抗原表位
    • 18
    • 8
    • 8
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 59
    • 20
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    人, 小鼠, 小鸡
    宿主
    • 48
    • 9
    • 2
    • 1
    克隆类型
    • 51
    • 9
    多克隆
    标记
    • 38
    • 6
    • 5
    • 4
    • 4
    • 3
    This PTK7 antibody is un-conjugated
    应用范围
    • 50
    • 37
    • 24
    • 13
    • 9
    • 8
    • 5
    • 4
    • 3
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody reacts specifically with Human 112 kDa CCK-4.
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Chicken.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography on Protein A
    免疫原
    Synthetic peptide derived from Human N-terminal region of CCK-4
    Top Product
    Discover our top product PTK7 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    Restore in distilled water.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer
  • 抗原
    PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))
    别名
    PTK7 / CCK4 (PTK7 产品)
    别名
    PTK7 antibody, CCK-4 antibody, CCK4 antibody, Srf antibody, 8430404F20Rik antibody, chz antibody, mPTK7/CCK4 antibody, KLG antibody, protein tyrosine kinase 7 (inactive) antibody, protein tyrosine kinase 7 antibody, PTK7 protein tyrosine kinase 7 antibody, PTK7 antibody, Ptk7 antibody
    背景
    PTK7 is a member of the receptor tyrosine kinase family otherwise known as Colon Carcinoma Kinase 4 (CCK4). PTK7 is highly expressed in the kidney, liver, lung, pancreas and melanocytes with weaker expression being detected in the thyroid gland, ovaries, brain, heart and skeletal muscle. PTK7 may play a role in embryonic development. It is thought to function as a cell adhesion molecule and as a novel regulator of the planar cell polarity (PCP) pathway in vertebrates. Studies also suggest that PTK7 may be involved in the tumour progression. A loss of PTK7 expression has been observed in melanoma cell lines, whereas increased levels of PTK7 have been detected in high-throughput acute myeloid leukaemia samples. In addition, PTK7 is not expressed in normal colon but has been detected in colon carcinomas and as such is a potential marker for tumour progression.Synonyms: CCK-4, Colon carcinoma kinase 4, Tyrosine-protein kinase-like 7
    基因ID
    5754
    NCBI登录号
    NP_002812
    途径
    RTK signaling, Tube Formation
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