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PTK7 抗体 (N-Term)

This anti-PTK7 antibody is a 兔 多克隆 antibody detecting PTK7 in WB, EIA 和 IHC (fro). Suitable for 人, 小鼠 和 小鸡.
产品编号 ABIN1108790
发货至: 中国

Quick Overview for PTK7 抗体 (N-Term) (ABIN1108790)

抗原

See all PTK7 抗体
PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

适用

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人, 小鼠, 小鸡

宿主

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克隆类型

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多克隆

标记

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This PTK7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    N-Term

    特异性

    This antibody reacts specifically with Human 112 kDa CCK-4.

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Chicken.
    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography on Protein A

    免疫原

    Synthetic peptide derived from Human N-terminal region of CCK-4
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    Restore in distilled water.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer
  • 抗原

    PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

    别名

    PTK7 / CCK4

    背景

    PTK7 is a member of the receptor tyrosine kinase family otherwise known as Colon Carcinoma Kinase 4 (CCK4). PTK7 is highly expressed in the kidney, liver, lung, pancreas and melanocytes with weaker expression being detected in the thyroid gland, ovaries, brain, heart and skeletal muscle. PTK7 may play a role in embryonic development. It is thought to function as a cell adhesion molecule and as a novel regulator of the planar cell polarity (PCP) pathway in vertebrates. Studies also suggest that PTK7 may be involved in the tumour progression. A loss of PTK7 expression has been observed in melanoma cell lines, whereas increased levels of PTK7 have been detected in high-throughput acute myeloid leukaemia samples. In addition, PTK7 is not expressed in normal colon but has been detected in colon carcinomas and as such is a potential marker for tumour progression.Synonyms: CCK-4, Colon carcinoma kinase 4, Tyrosine-protein kinase-like 7

    基因ID

    5754

    NCBI登录号

    NP_002812

    途径

    RTK signaling, Tube Formation
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