PROS1 抗体
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北京 101111
Quick Overview for PROS1 抗体 (ABIN1108756)
抗原
See all PROS1 (PROS) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Monoclonal antibody PS7 is specific for human Protein S (PS), a vitamin K-dependent plasma glycoprotein with a molecular weight of approximately 70 kDa. Allows specific detection of cells carrying PS by flow cytometry.
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity C Chromatography on Protein G
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亚型
- IgG2a
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anti-Protein S (PROS) (AA 481-667) antibody
PROS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein S (PROS) (N-Term) antibodyPROS 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein S (PROS) (AA 42-676) antibodyPROS 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein S (PROS) (AA 1-676) antibodyPROS 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein S (PROS) (AA 245-295) antibodyPROS 适用: 人, 大鼠, 小鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein S (PROS) (AA 405-676) antibodyPROS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein S (PROS) antibodyPROS 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein S (PROS) (AA 419-516) antibodyPROS 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein S (PROS) (AA 251-300) antibodyPROS 适用: 人, 大鼠, 小鼠, 犬, 马, Cow, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein S (PROS) (AA 416-646) antibodyPROS 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.02 % Sodium Azide, 0.1 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 2-8 °C.
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- PROS1 (PROS) (Protein S (PROS))
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背景
- In humans, PS is mainly synthesized by hepatocytes. Mature PS has a modular structure consisting of a Gla-domain containing a short aromatic stack, a region sensitive to cleavage by thrombin and factor Xa , 4 epidermal growth factor (EGF)-like domains, and a sex hormone-binding globulin-like region. The biologic function of PS thought to be of primary importance is its ability to enhance Activated Protein C-dependent proteolytic inactivation of factors Va and VIIIa, which are respectively the cofactors in the pro-thrombinase and tenase complexes of the coagulation cascade. In this way, PS plays an important role in regulating thrombin generation, and therefore controlling procoagulant activity. Crucial to the APC-dependent functions of PS is the high-affinity interaction between PS and negatively charged phospholipid surfaces, conferred by calcium-induced folding of the amino-terminal Gla-domain.Synonyms: PROS, Vitamin K-dependent protein S
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基因ID
- 5627
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NCBI登录号
- NP_000304
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UniProt
- P07225
抗原
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