PLGF 抗体 (N-Term)
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Quick Overview for PLGF 抗体 (N-Term) (ABIN1108665)
抗原
See all PLGF (PGF) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects Placenta growth factor / PGF (N-term). No cross reactivity with other proteins.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat.
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纯化方法
- Immunogen affinity purified
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免疫原
- Synthetic peptide corresponding to a sequence mapping near the N-terminal of human PLGF .Remarks: Sequence is different from the related rat sequence by two different amino acids.
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亚型
- IgG
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anti-Placenta Growth Factor (PGF) (Internal Region) antibody
PGF 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Placenta Growth Factor (PGF) (AA 166-221) antibodyPGF 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Placenta Growth Factor (PGF) (AA 19-170) antibodyPGF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Placenta Growth Factor (PGF) (AA 101-158) antibodyPGF 适用: 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Placenta Growth Factor (PGF) (AA 43-162) antibodyPGF 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Placenta Growth Factor (PGF) (AA 24-158) antibodyPGF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Placenta Growth Factor (PGF) antibodyPGF 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 1B6 unconjugated Recombinant Antibody
anti-Placenta Growth Factor (PGF) (AA 1-170) antibodyPGF 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Placenta Growth Factor (PGF) (AA 1-170) antibodyPGF 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Placenta Growth Factor (PGF) (AA 131-158) antibodyPGF 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- 1.2 % sodium acetate or neutral PBS. If 0.5 mL of PBS is used, the antibody concentration will be 100 μg/mL.
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缓冲液
- 50 % glycerol, 0.9 mg NaCl, 0.2 mg Na2HPO4
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- PLGF (PGF) (Placenta Growth Factor (PGF))
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别名
- Placenta Growth Factor / PGF
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背景
- Placental growth factor (PGF, also known as PLGF) codes for an angiogenic factor expressed in placental tissue that is similar to vascular permeability factor/vascular endothelial growth factor (VPF/VEGF). It is a glycosylated dimeric secreted protein able to stimulate endothelial cell growth in vitro. PGF is located on chromosome 14 and has been conserved in evolution. It belongs to the family of vascular endothelial growth factors (VEGFs) and binds to the flt-1 VEGF receptor. PLGF-2, which is a PLGF isoform, binds neuropilin-1 and 2 in a heparin-dependent manner. PGF regulates inter-and intra molecular cross talk between the VEGF RTKs Flt1 and Flk1 and stimulates the phosphorylation of specific Flt1 tyrosine residues and the expression of distinct downstream target genes. Moreover, it plays an important role in pathological angiogenic events and with exerting its biological activities through binding to VEGFR1.Synonyms: PGFL, PLGF, PlGF
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基因ID
- 5228
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NCBI登录号
- NP_002623
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UniProt
- P49763
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途径
- VEGFR1 Specific Signals
抗原
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