Paxillin 抗体 (C-Term)
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Quick Overview for Paxillin 抗体 (C-Term) (ABIN1108595)
抗原
See all Paxillin (PXN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 305-559, C-Term
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特异性
- This antibody reacts to Paxillin.
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纯化方法
- Affinity chromatography
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免疫原
- C-terminal part of recombinant chicken paxillin (amino acids 305-559)
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Restore with 1.2 % sodium acetate or neutral PBS
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浓度
- 0,1 mg/mL
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缓冲液
- 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Paxillin (PXN)
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别名
- Paxillin / PXN
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背景
- The paxillin gene can be alternatively spliced to include 1 of 2 alternative exons, generating beta and gamma isoforms. Paxillin is a 68- kDa focal adhesion protein that is phosphorylated on tyrosine residues in fibroblasts in response to transformation by v-src, treatment with platelet-derived growth factor, or cross-linking of integrins. The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal adhesions of Madin-Darby bovine kidney (MDBK) epithelial cells but is absent, like talin, from the cell-cell adherens junctions of these cells.Synonyms: FLJ16691
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基因ID
- 5829
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NCBI登录号
- NP_001074324
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UniProt
- P49023
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途径
- MAPK Pathway, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
抗原
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