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Paxillin 抗体 (C-Term)

The 小鼠 单克隆 anti-Paxillin antibody is suitable to detect Paxillin in samples from 人, 小鼠, 大鼠 和 小鸡. It has been validated for WB 和 IF.
产品编号 ABIN1108595
发货至: 中国
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Quick Overview for Paxillin 抗体 (C-Term) (ABIN1108595)

抗原

See all Paxillin (PXN) 抗体
Paxillin (PXN)

适用

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人, 小鼠, 大鼠, 小鸡

宿主

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小鼠

克隆类型

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单克隆

标记

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This Paxillin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)

克隆位点

PAX-14
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    AA 305-559, C-Term

    特异性

    This antibody reacts to Paxillin.

    纯化方法

    Affinity chromatography

    免疫原

    C-terminal part of recombinant chicken paxillin (amino acids 305-559)

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    Restore with 1.2 % sodium acetate or neutral PBS

    浓度

    0,1 mg/mL

    缓冲液

    1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Paxillin (PXN)

    别名

    Paxillin / PXN

    背景

    The paxillin gene can be alternatively spliced to include 1 of 2 alternative exons, generating beta and gamma isoforms. Paxillin is a 68- kDa focal adhesion protein that is phosphorylated on tyrosine residues in fibroblasts in response to transformation by v-src, treatment with platelet-derived growth factor, or cross-linking of integrins. The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal adhesions of Madin-Darby bovine kidney (MDBK) epithelial cells but is absent, like talin, from the cell-cell adherens junctions of these cells.Synonyms: FLJ16691

    基因ID

    5829

    NCBI登录号

    NP_001074324

    UniProt

    P49023

    途径

    MAPK Pathway, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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