NOS1 抗体 (N-Term)
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北京 101111
Quick Overview for NOS1 抗体 (N-Term) (ABIN1108474)
抗原
See all NOS1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-181, N-Term
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特异性
- This antibody reacts to NOS1 (1-181).
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纯化方法
- Affinity chromatography
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免疫原
- Protein A fusion protein
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亚型
- IgG1
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anti-Nitric Oxide Synthase 1, Neuronal (NOS1) (C-Term) antibody
Verified NOS1 适用: 人 IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Nitric Oxide Synthase 1, Neuronal (NOS1) (AA 53-247) antibodyNOS1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 1, Neuronal (NOS1) (AA 9-136) antibodyNOS1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 1, Neuronal (NOS1) (AA 17-153) antibodyNOS1 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2E11G6 unconjugated
anti-Nitric Oxide Synthase 1, Neuronal (NOS1) antibodyNOS1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Nitric Oxide Synthase 1, Neuronal (NOS1) (pSer852) antibodyNOS1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 1, Neuronal (NOS1) (AA 1213-1337) antibodyNOS1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 1, Neuronal (NOS1) (AA 51-150) antibodyNOS1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 1, Neuronal (NOS1) (AA 691-826) antibodyNOS1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 1, Neuronal (NOS1) (C-Term) antibodyNOS1 适用: 人 WB, IHC 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Restore with 1.2 % sodium acetate or neutral PBS
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浓度
- 0,1 mg/mL
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缓冲液
- 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))
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别名
- NOS1
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背景
- Nitric Oxide Synthase 1(NOS1,neuronal NOS,nNOS1) is a messenger molecule, mediating the effect ofendothelium-derived relaxing factor in blood vessels and the cytotoxic actions of macrophages, and playing a part in neuronal communication in the brain. It may be involved in neuronal cell death and damage in neurological illness. nNOS1 localized to the 12q24.2 region of human chromosome 12. It splice variant, expressed in testis, that encodes an NH2-terminal truncated protein of 1098 amino acids. nNOS cDNA clones were shown to contain different 5' terminal exons spliced to a common exon 2.Genomic cloning and sequence analysis demonstrate that the unique exons are positioned within 300 bp of each other but separated from exon 2 by an intron that is at least 20 kb in length. The neuronal isoform of nitric oxide synthase is highly expressed in mammalian skeletal muscle, it suggested a specific role for NOS1 in the local metabolic inhibition of alpha-adrenergic vasoconstriction in active skeletal muscle. The novel gaseous neuromediator nitric oxide is thought to play an important role in development and plasticity. Despite this, gene-knockout mice lacking neuronal (Type I) nitric oxide synthase exhibit relatively normal brain development and behavior.Synonyms: Constitutive NOS, NC-NOS, NOS type I, Neuronal NOS, Nitric Oxide Synthase, bNOS, nNOS
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基因ID
- 4842
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NCBI登录号
- NP_000611
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UniProt
- P29475
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途径
- Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction
抗原
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