PRG2 抗体
Quick Overview for PRG2 抗体 (ABIN110842)
抗原
See all PRG2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Specific for eosinophil major basic protein irrespective of the stages of eosinophil activation and can be regarded as an eosinophil marker. The antibody will recognize the 23.8 kDa secreted pro-form of MBP (Pregnancy associated MBP) and the 13.8 kDa mature form found in the matrix of the eosinophil large specific granule. Does not cross-react with horse, mouse or rat MBP.
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纯化方法
- Protein A chromatography
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亚型
- IgG1
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anti-Bone Marrow Proteoglycan (PRG2) (AA 17-222) antibody
PRG2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bone Marrow Proteoglycan (PRG2) (Internal Region) antibodyPRG2 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bone Marrow Proteoglycan (PRG2) (AA 151-195) antibodyPRG2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bone Marrow Proteoglycan (PRG2) (AA 1-222) antibodyPRG2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Bone Marrow Proteoglycan (PRG2) (AA 316-344) antibodyPRG2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB27160 unconjugated
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应用备注
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IHC with fresh frozen tissue (fix in methanol: acetone)IHC with formalin fixed paraffin-embedded tissue (treat with 0.1 % trypsin before blocking)Western blotELISA
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS with 0.09 % sodium azide as preservative and 0.1 % BSA as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
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- PRG2 (Bone Marrow Proteoglycan (PRG2))
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别名
- Proteoglycan 2
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背景
- PRG2 is a cytotoxin and helminthotoxin. It also induces noncytolytic histamine release from human basophils and is involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA. In pregnancy serum, the proform exists as a disulfide-linked 2:2 heterotetramer with PAPPA, as a disulfide-linked 2:2 heterotetramer with AGT, and as a complex (probably a 2:2:2 heterohexamer) with AGT and C3dg.Synonyms: BMPG, Bone marrow proteoglycan, EMBP, Eosinophil granule major basic protein, PRG2, Pregnancy-associated major basic protein
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基因ID
- 5553
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NCBI登录号
- NP_002719
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UniProt
- P13727
抗原
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