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Myeloperoxidase 抗体 (FITC)

This anti-Myeloperoxidase antibody is a 小鼠 单克隆 antibody detecting Myeloperoxidase in FACS 和 IF. Suitable for 人.
产品编号 ABIN1108346
发货至: 中国

Quick Overview for Myeloperoxidase 抗体 (FITC) (ABIN1108346)

抗原

See all Myeloperoxidase (MPO) 抗体
Myeloperoxidase (MPO)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Myeloperoxidase antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

266-6K2
  • 特异性

    Clone 266.6K2 reacts with the intracellular enzyme MPO. In a study comparing anti-MPO with other myeloid-reactive monoclonal antibodies such as anti-CD13, CD14, CD15 and CD33, a higher diagnostic sensitivity and specificity was found for AML using anti-MPO. In most patients, more MPO-positive cells were detected by anti-MPO than by cytochemical staining with Sudan black and standard peroxidase. Testing by flow cytometry using a fixation and permeabilization solution on whole blood from healthy donors showed the following values expressed in terms of % of the total leukocyte count: Product code: AM39035FC-N (anti-MPO FITC) n: 10 Mean % positive: 64,06 S.D.: 5,07 % CV: 7,92

    纯化方法

    Affinity chromatography

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C. Fluorochrome labelled product is photosensitive and should be protected from light.
  • 抗原

    Myeloperoxidase (MPO)

    别名

    Myeloperoxidase

    背景

    Myeloperoxidase (MPO) is an intracellular enzyme in peripheral blood granulocytes. Anti-MPO antibodies stain promyelocytes, myelocytes, metamyelocytes and mature neutrophil granulocytes in bone marrow. Monocytes are negative or slightly positive while eosinophils and lymphocytes are negative. Anti-MPO is used for the diagnosis of AML (acute myeloid leukemia). Non-myeloid leukemia (e.g. acute lymphoblastic leukemia) is usually non-reactive with anti-MPO.Synonyms: MPO

    基因ID

    4353

    NCBI登录号

    NP_000241

    UniProt

    P05164

    途径

    Chromatin Binding
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