Afadin 抗体 (AA 1814-1829)
Quick Overview for Afadin 抗体 (AA 1814-1829) (ABIN1108256)
抗原
See all Afadin (MLLT4) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1814-1829
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特异性
- This antibody detects L-Afadin.
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat, dog
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纯化方法
- Protein G
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免疫原
- Peptide 1814-1829 aa of rat l-afadin
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2 - 8 °C.
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- Afadin (MLLT4)
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别名
- MLLT4 / AF6 / Afadin
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背景
- Afadin is an actin filament-binding protein that is involved in cell-cell adherens junctions (AJs) which directly interacts with the alpha herpus virus receptor, a member of the immunoglobulin supergene family. Afadin is colocalized with nectin at cadherin-based cell-cell adherence junctions in various tissues and cell lines. L-Afadin has been isolated as an F-actin-binding protein from rat brain. L-afadin is ubiquitously expressed and specifically localized at zonula adherens (ZA) in epithelial cells and at cell-cell adherens junctions (AJs) in non-epithelial cells. L-afadin has a splice variant, named small intestine absorptive afadin (s-afadin) which is abundantly expressed in neural tissue.Synonyms: Myeloid/lymphoid Or Mixed-lineage Leukemia Translocated To 4, Protein AF-6
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基因ID
- 26955
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NCBI登录号
- NP_037349
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UniProt
- O35889
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途径
- Cell-Cell Junction Organization
抗原
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