MHC Class II Antigen I Ak,d,b,q,r 抗体
This 大鼠 单克隆 antibody specifically detects MHC Class II Antigen I Ak,d,b,q,r in FACS 和 IHC (fro). It exhibits reactivity toward 小鼠 和 人.
产品编号 ABIN1108234
发货至:
中国
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Quick Overview for MHC Class II Antigen I Ak,d,b,q,r 抗体 (ABIN1108234)
抗原
MHC Class II Antigen I Ak,d,b,q,r
适用
小鼠, 人
宿主
大鼠
克隆类型
单克隆
标记
非结合性
应用范围
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
克隆位点
ER-TR3
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交叉反应 （详细）
- Species reactivity (tested):Mouse, human (tonsil)
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纯化方法
- Protein G
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亚型
- IgG2b
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anti-MHC Class II Antigen I Ak,d,b,q,r antibody (Biotin)
适用: 小鼠 FACS, IHC (fro) 宿主: 大鼠 Monoclonal ER-TR3 Biotin
anti-MHC Class II Antigen I Ak,d,b,q,r antibody (FITC)适用: 小鼠 FACS, IHC (fro) 宿主: 大鼠 Monoclonal ER-TR3 FITC
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at < -20 °C for at least 6 months.
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有效期
- 6 months
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- MHC Class II Antigen I Ak,d,b,q,r
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别名
- MHC Class II (I-A K,b,d,q,r)
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背景
- MHC class II molecules are heterodimers of non-covalently associated alpha (31-34 kDa) and beta (26-29 kDa) chains. Major histocompatibility complex class II antigen presentation requires the participation of lysosomal proteases in two convergent processes. First, the antigens endocytosed by the antigen-presenting cells must be broken down into antigenic peptides. Second, class II molecules are synthesized with their peptide-binding site blocked by invariant chain (Ii), and they acquire the capacity to bind antigens only after Ii has been degraded in the compartments where peptides reside. MHC class II molecules present exogenously derived antigen to CD4+ T lymphocytes, which are usually T helper cells. CD4 interacts with non-polymorphic residues of MHC Class II.
抗原
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