MBP/MBL 抗体
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北京 101111
Quick Overview for MBP/MBL 抗体 (ABIN1108118)
抗原
See all MBP/MBL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应 （详细）
- Species reactivity (tested):Human.
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亚型
- IgG1
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anti-Mannan Binding Protein/Mannan Binding Lectin (MBP/MBL) (AA 31-130) antibody
MBP/MBL 适用: 人, 大鼠 ICC, IHC (fro), ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mannan Binding Protein/Mannan Binding Lectin (MBP/MBL) antibodyMBP/MBL 适用: 人, 小鼠, 大鼠, Cow, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mannan Binding Protein/Mannan Binding Lectin (MBP/MBL) antibodyMBP/MBL 适用: 小鼠 WB, IHC (fro), EIA, IF 宿主: 大鼠 Monoclonal 14D12 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0,1 mg/mL
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缓冲液
- PBS, 0,02 % sodium azide, 0,1 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- MBP/MBL (Mannan Binding Protein/Mannan Binding Lectin (MBP/MBL))
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别名
- Mannan Binding Protein
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背景
- Mannose Binding Lectin (MBL) also called mannose- or mannan-binding protein (MBP) is a member of the group of Collectins. MBL is an oligomeric lectin that recognizes carbohydrates as mannose and N-acetylglucosamine on pathogens. MBL contains a cysteine rich, a collagen like and a carbohydrate recognition domain. It forms a complex with C1r/C1s like serine proteases designated MASPs that proteolytically cleave C4, C2 and C3. MBL is able to activate the complement pathway independent of the classical and alternative complement activation pathways. The MBL-MASP pathway (better known as the lectin pathway) is antibody and C1q-independent. MBL exhibits complement-dependent antibacterial activity and acts directly as an opsonic and therefore plays an important role in innate immunity. MBL is synthesized by hepatocytes and has been isolated from the liver or serum of various vertebrate species.Synonyms: MBL, MBL2, MBP, MBP-C, MBP1, Mannan-binding protein, Mannose-binding lectin, Mannose-binding protein C
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基因ID
- 9606
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UniProt
- P11226
抗原
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