LTBR 抗体
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北京 101111
Quick Overview for LTBR 抗体 (ABIN1108069)
抗原
See all LTBR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应 （详细）
- Species reactivity (tested):Mouse
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纯化方法
- Protein G
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亚型
- IgG2a
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anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 66-215) antibody
LTBR 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 31-227) antibodyLTBR 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1D1C5C8 unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 128-395) antibodyLTBR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (N-Term) antibodyLTBR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 31-227) antibodyLTBR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 31-224) antibodyLTBR 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 66-215) antibodyLTBR 适用: 人 WB 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) antibodyKD Validated LTBR 适用: 人 WB 宿主: 小鼠 Monoclonal 24GB6730 unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (AA 351-435) antibodyLTBR 适用: 人, 小鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) (N-Term) antibodyLTBR 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % bovine serum albumin
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储存条件
- 4 °C
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储存方法
- Store at 2 - 8 °C.
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- LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))
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别名
- LTBR / TNFR3
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背景
- LTbetaR is a member of the tumor necrosis factor (TNF) family. This receptor can be activated by its functional ligands lymphotoxin-alpha1-beta2 (LT-alpha1beta2) and LIGHT and is critically involved in controlling bacterial infections. In Mycobacterium infection, its role is related to bactericidal granuloma formation in the spleen, macrophage differentiation and the maintenance of the appropriate Th1/Th2 cytokine balance. In CMV infection, LTbetaR signaling induces the expression of IFN-beta in infected fibroblasts, resulting in viral stasis. LTbetaR plays an important role in lymphoid organogenesis and tumor development. The receptor is expressed on fibroblasts and stromal cells and at low levels in some myeloid cell lines. In the adult animal, the LTbetaR seems to be necessary for maintaining the splenic architecture and aspects of Ig formation and B cell follicular structure. When the LT-alpha1beta2/LTbetaR pathway is disrupted by genetic deletion, mice completely lack Peyer's patches. Also, LTbetaR induces cell death in some adenocarcinoma tumor lines in the presence of IFNgamma.Synonyms: D12S370, Lymphotoxin-beta receptor, TNF-R3, TNFCR, TNFRSF3, Tumor necrosis factor C receptor, Tumor necrosis factor receptor 2-related protein, Tumor necrosis factor receptor 3, Tumor necrosis factor receptor superfamily member 3, Tumor necrosis factor receptor type III
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基因ID
- 17000
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NCBI登录号
- NP_034866
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UniProt
- P50284
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途径
- NF-kappaB Signaling
抗原
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