LRP5 抗体
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北京 101111
Quick Overview for LRP5 抗体 (ABIN1108063)
抗原
See all LRP5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes LRP5
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Purified
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, 0.05 % Sodium Azide, 0.5 % protein stabilizer
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
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别名
- LRP5
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背景
- This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.Synonyms: LRP-5, LRP7, Low-density lipoprotein receptor-related protein 5
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分子量
- 179 kDa
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基因ID
- 4041
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途径
- WNT signaling, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
抗原
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