Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
1.0 mg/mL
缓冲液
PBS, 0.05 % Sodium Azide, 0.5 % protein stabilizer
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
抗原
LRP5
(Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
别名
LRP5
背景
This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.Synonyms: LRP-5, LRP7, Low-density lipoprotein receptor-related protein 5