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Lamin B1 抗体 (C-Term)

The 兔 多克隆 anti-Lamin B1 antibody is suitable to detect Lamin B1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IP, IF, IHC (p) 和 IHC (fro).
产品编号 ABIN1108013
发货至: 中国
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Quick Overview for Lamin B1 抗体 (C-Term) (ABIN1108013)

抗原

See all Lamin B1 (LMNB1) 抗体
Lamin B1 (LMNB1)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Lamin B1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    C-Term

    特异性

    This antibody detects Lamin Beta at C-term. No cross reactivity with other proteins.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Immunogen affinity purified

    免疫原

    Synthetic peptide corresponding to a sequence at the C-terminal of human Lamin B .Remarks: Sequence is different from the related rat and mouse sequence by three amino acids.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    缓冲液

    5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Lamin B1 (LMNB1)

    别名

    Lamin-B1 (LMNB1)

    背景

    Lamins are the major components of the nuclear lamina which underlies the nuclear envelope of eukaryotic cells. lamin B is a structural component of the long-sought-after spindle matrix that promotes microtubule assembly and organization in mitosis. Inspection of the deduced amino acid sequence of lamin B revealed the presence in coil 1B of the alpha-helical domain of a leucine heptad repeat region.Lamin B assembled into a matrix-like network in mitosis through a process that depended on the presence of the guanosine triphosphate-bound form of the small guanosine triphosphatase Ran.Synonyms: LMN2, LMNB, Lamin B1, Lamin B1/B2, Lamin B2

    基因ID

    4001

    NCBI登录号

    NP_005564

    UniProt

    P20700

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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