This antibody detects Lamin Beta at C-term. No cross reactivity with other proteins.
交叉反应 (详细)
Species reactivity (tested):Human, mouse, rat
纯化方法
Immunogen affinity purified
免疫原
Synthetic peptide corresponding to a sequence at the C-terminal of human Lamin B .Remarks: Sequence is different from the related rat and mouse sequence by three amino acids.
This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
抗原
Lamin B1 (LMNB1)
别名
Lamin-B1 (LMNB1)
背景
Lamins are the major components of the nuclear lamina which underlies the nuclear envelope of eukaryotic cells. lamin B is a structural component of the long-sought-after spindle matrix that promotes microtubule assembly and organization in mitosis. Inspection of the deduced amino acid sequence of lamin B revealed the presence in coil 1B of the alpha-helical domain of a leucine heptad repeat region.Lamin B assembled into a matrix-like network in mitosis through a process that depended on the presence of the guanosine triphosphate-bound form of the small guanosine triphosphatase Ran.Synonyms: LMN2, LMNB, Lamin B1, Lamin B1/B2, Lamin B2