Lamin B1 抗体 (C-Term)
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Quick Overview for Lamin B1 抗体 (C-Term) (ABIN1108013)
抗原
See all Lamin B1 (LMNB1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects Lamin Beta at C-term. No cross reactivity with other proteins.
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Immunogen affinity purified
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免疫原
- Synthetic peptide corresponding to a sequence at the C-terminal of human Lamin B .Remarks: Sequence is different from the related rat and mouse sequence by three amino acids.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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缓冲液
- 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Lamin B1 (LMNB1)
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别名
- Lamin-B1 (LMNB1)
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背景
- Lamins are the major components of the nuclear lamina which underlies the nuclear envelope of eukaryotic cells. lamin B is a structural component of the long-sought-after spindle matrix that promotes microtubule assembly and organization in mitosis. Inspection of the deduced amino acid sequence of lamin B revealed the presence in coil 1B of the alpha-helical domain of a leucine heptad repeat region.Lamin B assembled into a matrix-like network in mitosis through a process that depended on the presence of the guanosine triphosphate-bound form of the small guanosine triphosphatase Ran.Synonyms: LMN2, LMNB, Lamin B1, Lamin B1/B2, Lamin B2
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基因ID
- 4001
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NCBI登录号
- NP_005564
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UniProt
- P20700
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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