Optimal working dilution should be determined by the investigator.
限制
仅限研究用
浓度
1.0 mg/mL
缓冲液
PBS without carriers and preservatives
储存液
Without preservative
储存条件
4 °C
储存方法
Store the antibody undiluted at 2-8 °C.
抗原
IL-24 (IL24)
(Interleukin 24 (IL24))
别名
Interleukin-24 / IL24
背景
Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.Synonyms: IL-24, MDA7, Melanoma differentiation-associated gene 7 protein, ST16, Suppression of tumorigenicity 16 protein