IL-24 抗体
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北京 101111
Quick Overview for IL-24 抗体 (ABIN1107832)
抗原
See all IL-24 (IL24) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This Monoclonal antibody recognises both natural and recombinant Human IL-24 (Interleukin-24) also known as MDA-7 or TH2-specific cytokine FISP.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Ion Exchange Chromatography
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免疫原
- Recombinant Human IL-24. Myeloma X63/AG.8653 x Balb/c node cells.
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS without carriers and preservatives
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储存液
- Without preservative
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- IL-24 (IL24) (Interleukin 24 (IL24))
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别名
- Interleukin-24 / IL24
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背景
- Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.Synonyms: IL-24, MDA7, Melanoma differentiation-associated gene 7 protein, ST16, Suppression of tumorigenicity 16 protein
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基因ID
- 11009
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NCBI登录号
- NP_001172085
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UniProt
- Q13007
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途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy
抗原
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