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IL23A 抗体

IL23A 适用: 人 IHC (p), Func 宿主: 小鼠 Monoclonal B-Z23 unconjugated
产品编号 ABIN1107827
发货至: 中国
  • 抗原 See all IL23A 抗体
    IL23A (Interleukin 23, alpha subunit p19 (IL23A))
    适用
    • 43
    • 19
    • 8
    • 1
    宿主
    • 36
    • 7
    • 2
    • 1
    小鼠
    克隆类型
    • 39
    • 7
    单克隆
    标记
    • 32
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL23A antibody is un-conjugated
    应用范围
    • 32
    • 20
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func)
    特异性
    This antibody recognizes both recombinant and natural IL-23, p19 sub-unit.
    纯化方法
    Ion Exchange Chromatography
    过滤
    0.22 μm filtered
    免疫原
    Recombinant Human IL-23 (sub-unit p19)
    克隆位点
    B-Z23
    亚型
    IgG1
    Top Product
    Discover our top product IL23A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate-buffered saline. Sterile-filtered through 0.22 μm and treated to remove endotoxins. Carrier and preservative free.
    储存液
    Without preservative
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    IL23A (Interleukin 23, alpha subunit p19 (IL23A))
    别名
    Interleukin-23 alpha / IL23A (IL23A 产品)
    别名
    IL-23 antibody, IL-23A antibody, IL23P19 antibody, P19 antibody, SGRF antibody, FIL1 antibody, FIL1(ZETA) antibody, FIL1Z antibody, IL-1F7 antibody, IL-1H antibody, IL-1H4 antibody, IL-1RP1 antibody, IL-37 antibody, IL1F7 antibody, IL1H4 antibody, IL1RP1 antibody, p19 antibody, il23p19 antibody, IL23 antibody, interleukin 23 subunit alpha antibody, interleukin 37 antibody, interleukin 23, alpha subunit p19 antibody, IL23A antibody, IL37 antibody, Il23a antibody
    背景
    The p19 shares sequence similarity with IL-6 subfamily members and is distantly related to the p35 subunit of IL-12. It shows no biological activity by itself, instead, it combines with the p40 subunit of IL-12 to form a biologically active, composite cytokine, IL-23. IL-23 shares some in vivo functions with IL-12, including the activation of the transcription factor Stat4. Similar to IL-12, human IL-23 stimulates IFN-g production and proliferation in PHA blast T cells, as well as in CD45RO (memory) T cells. Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death.Synonyms: IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF
    基因ID
    51561
    NCBI登录号
    NP_057668
    UniProt
    Q9NPF7
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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