IL23A 抗体
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北京 101111
Quick Overview for IL23A 抗体 (ABIN1107827)
抗原
See all IL23A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes both recombinant and natural IL-23, p19 sub-unit.
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纯化方法
- Ion Exchange Chromatography
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过滤
- 0.22 μm filtered
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免疫原
- Recombinant Human IL-23 (sub-unit p19)
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate-buffered saline. Sterile-filtered through 0.22 μm and treated to remove endotoxins. Carrier and preservative free.
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储存液
- Without preservative
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- IL23A (Interleukin 23, alpha subunit p19 (IL23A))
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别名
- Interleukin-23 alpha / IL23A
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背景
- The p19 shares sequence similarity with IL-6 subfamily members and is distantly related to the p35 subunit of IL-12. It shows no biological activity by itself, instead, it combines with the p40 subunit of IL-12 to form a biologically active, composite cytokine, IL-23. IL-23 shares some in vivo functions with IL-12, including the activation of the transcription factor Stat4. Similar to IL-12, human IL-23 stimulates IFN-g production and proliferation in PHA blast T cells, as well as in CD45RO (memory) T cells. Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death.Synonyms: IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF
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基因ID
- 51561
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NCBI登录号
- NP_057668
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UniProt
- Q9NPF7
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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