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IFNA 抗体

IFNA 适用: 人 Neut 宿主: 小鼠 Monoclonal #14 unconjugated
产品编号 ABIN1107768
发货至: 中国
  • 抗原 See all IFNA 抗体
    IFNA (Interferon alpha (IFNA))
    适用
    • 32
    • 21
    • 11
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 65
    • 25
    • 4
    • 2
    • 1
    小鼠
    克隆类型
    • 70
    • 26
    单克隆
    标记
    • 49
    • 14
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This IFNA antibody is un-conjugated
    应用范围
    • 92
    • 39
    • 28
    • 28
    • 26
    • 26
    • 21
    • 13
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Neutralization (Neut)
    无交叉反应
    小鼠
    交叉反应 (详细)
    Species reactivity (tested):Human.
    内毒素水平
    < 10 ng/mg of antibody, as determined by the LAL assay
    免疫原
    Human IFN-alpha (purified)
    克隆位点
    #14
    亚型
    IgG1
    Top Product
    Discover our top product IFNA Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS without preservatives
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store (in aliquots) at -20 °C.
  • 抗原
    IFNA (Interferon alpha (IFNA))
    别名
    Interferon alpha (IFN Alpha) (IFNA 产品)
    别名
    IFN-alphaO antibody, IFN-ALPHA-1 antibody, IFN1@ antibody, Ifa antibody, Ifa8 antibody, interferon alpha 16 antibody, interferon, alpha 1 antibody, interferon alpha antibody, interferon-alpha antibody, IFNA16 antibody, IFNA1 antibody, Ifna antibody, IFNA antibody
    背景
    The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms. Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species. Interferon alpha is produced primarily by plasmacytoid dendritic cells and is a potent component of the anti viral innate immune response, it modulates adaptive immunity. The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent.Synonyms: B Cell Interferon, IFN-alpha, IFNA, Interferon-alpha, Leukocyte Interferon, Type I Interferon
    途径
    JAK/STAT Signaling, TLR signaling, Hepatitis C, Inflammasome
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