IFNA 抗体
Quick Overview for IFNA 抗体 (ABIN1107768)
抗原
See all IFNA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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无交叉反应
- 小鼠
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交叉反应 （详细）
- Species reactivity (tested):Human.
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内毒素水平
- < 10 ng/mg of antibody, as determined by the LAL assay
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免疫原
- Human IFN-alpha (purified)
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亚型
- IgG1
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anti-Interferon alpha (IFNA) (AA 28-227) antibody
IFNA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) antibodyIFNA 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 24-192) antibodyIFNA 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 24-189) antibodyIFNA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 1-187) antibodyIFNA 适用: 豚鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 24-181) antibodyIFNA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) antibodyIFNA 适用: 大鼠 FACS 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 24-181) antibodyIFNA 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Interferon alpha (IFNA) (AA 47-191) antibodyIFNA 适用: 小鸡 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 23-187) antibodyIFNA 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS without preservatives
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store (in aliquots) at -20 °C.
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- IFNA (Interferon alpha (IFNA))
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别名
- Interferon alpha (IFN Alpha)
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背景
- The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms. Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species. Interferon alpha is produced primarily by plasmacytoid dendritic cells and is a potent component of the anti viral innate immune response, it modulates adaptive immunity. The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent.Synonyms: B Cell Interferon, IFN-alpha, IFNA, Interferon-alpha, Leukocyte Interferon, Type I Interferon
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途径
- JAK/STAT Signaling, TLR signaling, Hepatitis C, Inflammasome
抗原
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