Histone H2B 抗体
Quick Overview for Histone H2B 抗体 (ABIN1107547)
抗原
See all Histone H2B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat, hamster
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纯化方法
- Protein A agarose
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免疫原
- Protein fraction extracted from the mitotic chromosome
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亚型
- IgG2b
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anti-Histone H2B (acLys15) antibody
适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone H2B (acLys5) antibody适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone H2B (acLys12) antibody适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone H2B (acLys5) antibody适用: 人 WB, IHC, IF, ChIP, IP 宿主: 兔 Polyclonal unconjugated
anti-Histone H2B (acLys12) antibody适用: 人 WB, IHC, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Histone H2B (acLys20) antibody适用: 人 WB, ELISA, IF, ICC, ChIP, IP 宿主: 兔 Polyclonal unconjugated
anti-Histone H2B (meLys5) antibody适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone H2B (acLys5) antibody适用: 人 WB, ChIP, DB, ChIP-seq 宿主: 兔 Polyclonal unconjugated
anti-Histone H2B (AA 1-126) antibody适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Histone H2B (acLys120) antibody适用: 人 WB, ChIP, DB, ChIP-seq 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2, without preservatives
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store (in aliquots) at -20 °C.
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- Histone H2B
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背景
- The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The N-terminal tail of core histones undergoes multiple different post-translational modifications including acetylation, phosphorylation, ubiquitination, methylation, and ADP-ribosylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. Acetylation of histone H2B was suppressed to greater extent than that of the others, with histone H3 being relatively least affected. The analysis of acetylation status of each of the four lysine sites at the N-terminal tail of histone H2B revealed decreases consistent with those observed in the total acetylation patterns, with the K12 and K20 residues being markedly more affected than K5 and K15 residues.Synonyms: H2B Histone Family, HIST1H2B
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分子量
- 14 kDa
抗原
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