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Histone H2A 抗体

适用: 人, 大鼠, 小鼠, Hamster WB, IF, IP 宿主: 小鼠 Monoclonal C10037 unconjugated
产品编号 ABIN1107544
发货至: 中国
  • 抗原 See all Histone H2A 抗体
    Histone H2A
    适用
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    人, 大鼠, 小鼠, Hamster
    宿主
    • 82
    • 1
    小鼠
    克隆类型
    • 71
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    单克隆
    标记
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    This Histone H2A antibody is un-conjugated
    应用范围
    • 50
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    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat, hamster
    纯化方法
    Protein A agarose
    免疫原
    Protein fraction extracted from the mitotic chromosome
    克隆位点
    C10037
    亚型
    IgG2b
    Top Product
    Discover our top product Histone H2A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS
    储存液
    Azide free
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store (in aliquots) at -20 °C.
  • 抗原
    Histone H2A
    Abstract
    Histone H2A 产品
    别名
    5499 antibody, CG5499 antibody, Dmel\\CG5499 antibody, H2A antibody, H2A.F/Z antibody, H2A.X antibody, H2A.Z antibody, H2AV antibody, H2AV_DROM antibody, H2AX antibody, H2AZ antibody, H2Av antibody, H2AvD antibody, H2a.V antibody, H2av antibody, H2avD antibody, HIS antibody, HIS2AV antibody, HIS2AVD antibody, His antibody, His2 antibody, His2AV antibody, His2AvD antibody, HisH2Av antibody, Hist antibody, Hist2av antibody, gamma-H2Av antibody, gamma-HIS2AV antibody, gamma-His2Av antibody, gammaH2Av antibody, h2AvD antibody, his antibody, l(3)05146 antibody, l(3)810 antibody, l(3)97Dd antibody, l(3)L1602 antibody, DDBDRAFT_0205974 antibody, DDBDRAFT_0216271 antibody, DDB_0205974 antibody, DDB_0216271 antibody, RGD1564767 antibody, H2a-221 antibody, H2A-III antibody, HIST1H2AA antibody, Histone H2A variant antibody, putative histone H2A antibody, histone H2A antibody, histone cluster 1 H2A family member F antibody, histone H2A-like antibody, histone cluster 1, H2af antibody, histone2A1 antibody, histone cluster 1, H2A, III antibody, histone cluster 1, H2ac antibody, His2Av antibody, LMJF_17_0280 antibody, H2AX antibody, Hist1h2af antibody, LOC100425378 antibody, his2a1 antibody, HIST1H2A3 antibody, HIST1H2AC antibody, h2a-A antibody
    背景
    The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The N-terminal tail of core histones undergoes multIPPle different post-translational modifications including acetylation, phosphorylation, ubiquitination, methylation and ADP-ribosylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. The role of histone variants, and specially those of H3 and H2A, in various nuclear processes has been long appreciated. There are at least three different families of H2A variants present in a variety of organisms from yeast to mammals, and the degree of conservation among members of each family is greater than that of the canonical H2A. H2AX is thought to play a role in DNA double-strand break repair, the serine in the SQEY motif of H2AX is phosphorylated at the site of the DNA damage and serves as a signal for the recruitment of repair proteins. Macro H2A1, another H2A variant, has been shown to have a role in X-chromosome inactivation and dosage compensation in mammals, where it is found to localize to the inactive X after silencing has been established.Synonyms: H2A Histone Family, HIST1H2A
    分子量
    14 kDa
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