Histone H2A 抗体
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北京 101111
Quick Overview for Histone H2A 抗体 (ABIN1107544)
抗原
See all Histone H2A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat, hamster
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纯化方法
- Protein A agarose
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免疫原
- Protein fraction extracted from the mitotic chromosome
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亚型
- IgG2b
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anti-Histone H2A (acLys5) antibody
适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone H2A (pSer139) antibody适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Histone H2A (H2AK95ac) antibody适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB6080 unconjugated Recombinant Antibody
anti-Histone H2A (acLys9) antibody适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone H2A (H2AK9ac) antibody适用: 人 ELISA, IF, ICC 宿主: 兔 Monoclonal 3H5 unconjugated Recombinant Antibody
anti-Histone H2A antibody适用: 人 WB, ELISA, IF 宿主: 兔 Monoclonal 1H12 unconjugated Recombinant Antibody
anti-Histone H2A (AA 1-128) antibody适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Histone H2A (H2AY39oh) antibody适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB6085 unconjugated Recombinant Antibody
anti-Histone H2A (H2AK118me1) antibody适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB6330 unconjugated Recombinant Antibody
anti-Histone H2A (pThr121) antibody适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS
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储存液
- Azide free
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store (in aliquots) at -20 °C.
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- Histone H2A
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背景
- The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The N-terminal tail of core histones undergoes multIPPle different post-translational modifications including acetylation, phosphorylation, ubiquitination, methylation and ADP-ribosylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. The role of histone variants, and specially those of H3 and H2A, in various nuclear processes has been long appreciated. There are at least three different families of H2A variants present in a variety of organisms from yeast to mammals, and the degree of conservation among members of each family is greater than that of the canonical H2A. H2AX is thought to play a role in DNA double-strand break repair, the serine in the SQEY motif of H2AX is phosphorylated at the site of the DNA damage and serves as a signal for the recruitment of repair proteins. Macro H2A1, another H2A variant, has been shown to have a role in X-chromosome inactivation and dosage compensation in mammals, where it is found to localize to the inactive X after silencing has been established.Synonyms: H2A Histone Family, HIST1H2A
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分子量
- 14 kDa
抗原
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