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Histone H1 抗体

Cited in 4+ publications. The 小鼠 单克隆 anti-Histone H1 antibody (Clone AE-4) (ABIN1107537) specifically detects Histone H1 in IF, WB, IHC (p), IP, IHC (fro) 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN1107537
发货至: 中国
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Quick Overview for Histone H1 抗体 (ABIN1107537)

抗原

See all Histone H1 抗体
Histone H1

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Histone H1 antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

克隆位点

AE-4
  • 交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Purified

    免疫原

    A BALB/c mouse was immunized with Human leukemia biopsy cells. The isolated splenocytes were fused with mouse myeloma cells.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or -20 °C for longer.
  • Schlegel, Meir, Heupel, Holthöfer, Leube, Waschke: "Desmoglein 2-mediated adhesion is required for intestinal epithelial barrier integrity." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 298, Issue 5, pp. G774-83, (2010) (PubMed).

    Poschmann, Sitek, Sipos, Ulrich, Wiese, Stephan, Warscheid, Klöppel, Vander Borght, Ramaekers, Meyer, Stühler: "Identification of proteomic differences between squamous cell carcinoma of the lung and bronchial epithelium." in: Molecular & cellular proteomics : MCP, Vol. 8, Issue 5, pp. 1105-16, (2009) (PubMed).

    Straub, Stoeffel, Heid, Zimbelmann, Schirmacher: "Differential pattern of lipid droplet-associated proteins and de novo perilipin expression in hepatocyte steatogenesis." in: Hepatology (Baltimore, Md.), Vol. 47, Issue 6, pp. 1936-46, (2008) (PubMed).

    Andersson, Karlsson, Carlsson, Pütsep: "Expression of granule-associated proteins in neutrophils from patients with severe congenital neutropenia." in: Blood, Vol. 110, Issue 7, pp. 2772-3; author reply 2773-4, (2007) (PubMed).

  • 抗原

    Histone H1

    背景

    The histone proteins serve as a structural scaffold for the organisation of nuclear DNA into chromatin. In eucariotic cells there are 4 core histone proteins, H2A, H2B, H3 and H4 that asseble to form an octamer round which the DNA is wrapped in a sequence dependant manner. The resulting complex is known as a nucleosome and is the basic subunit of chromatin. Histone H1 acts as a linker and binds to each nucleosome, and by self affinity, links these nucleosomes together resulting in the 30 nm chromatin fiber.Synonyms: H1 Histone Family, H1F4, H1F5, Histone H1a, Histone H1b
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