Galectin 3 抗体
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Quick Overview for Galectin 3 抗体 (ABIN1107301)
抗原
See all Galectin 3 (LGALS3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with galectin-3, a 30 kDa protein.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse
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纯化方法
- Protein G
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亚型
- IgG1
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anti-Galectin 3 (LGALS3) (AA 1-250) antibody
LGALS3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Galectin 3 (LGALS3) (AA 1-250) antibodyLGALS3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Galectin 3 (LGALS3) antibodyLGALS3 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Galectin 3 (LGALS3) antibodyLGALS3 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Galectin 3 (LGALS3) (AA 1-250) antibodyLGALS3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G8 unconjugated
anti-Galectin 3 (LGALS3) (AA 153-264) antibodyLGALS3 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Galectin 3 (LGALS3) (AA 151-250) antibodyLGALS3 适用: 人, 小鼠 ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Galectin 3 (LGALS3) (AA 1-262) antibodyLGALS3 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Galectin 3 (LGALS3) (AA 1-250) antibodyLGALS3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Galectin 3 (LGALS3) antibodyLGALS3 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Monoclonal 4E1 unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % bovine serum albumin
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储存条件
- 4 °C
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储存方法
- Store at 2 - 8 °C.
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- Galectin 3 (LGALS3)
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别名
- Galectin-3
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物质类
- Chemical
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背景
- Galectin-3 is a member of the galectin family. The protein is composed of three domains: a small amino-terminal domain, a carboxyl-terminal carbohydrate recognition domain (CRD) and amino-terminal domain containing repeating elements. Galectin-3 is normally distributed in epithelia of many organs and various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. The expression is also affected by neoplastic transformation: up-regulated in certain types of lymphomas and thyroid carcinoma, while down-regulated in other types of malignancies, such as colon, breast, ovarian and uterine carcinomas. Galectin-3 has been shown to function through both intracellular and extracellular actions. Related to its intracellular functions, galectin-3 has been identified as a component of heterogeneous nuclear ribonuclear protein (hnRNP), a factor in pre-mRNA splicing, and has been found to control cell cycle and prevent T cell apoptosis. On the other hand, this protein has also been demonstrated to function as extracellular molecule in activating various types of cells, including monocytes/macrophages, mast cells, neutrophils and lymphocytes. Galectin-3 has been shown to mediate cell-cell and cell-extracellular matrix interactions.Synonyms: 35 kDa lectin, CBP35, Carbohydrate-binding protein 35, GAL3, GALBP, Galactose-specific lectin 3, IgE-binding protein, L-31, L-34 galactoside-binding lectin, Laminin-binding protein, Lectin L-29, Lgals3, Mac-2
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基因ID
- 3958
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NCBI登录号
- NP_002297
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UniProt
- P17931
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途径
- RTK signaling
抗原
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