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Estrogen Receptor alpha 抗体

The 小鼠 单克隆 anti-Estrogen Receptor alpha antibody (Clone 2B7) (ABIN1107144) specifically detects Estrogen Receptor alpha in WB, IHC (p) 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN1107144
发货至: 中国
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Quick Overview for Estrogen Receptor alpha 抗体 (ABIN1107144)

抗原

See all Estrogen Receptor alpha (ESR1) 抗体
Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Estrogen Receptor alpha antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

克隆位点

2B7
  • 特异性

    This antibody recognizes ER-alpha.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Purified

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS, 0,03 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

    别名

    Estrogen Receptor alpha

    背景

    The estrogen receptor (ER) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Alternative splicing results in several ER mRNA transcripts, which differ primarily in their 5-prime untranslated regions. Two isoforms of the human ER, ERA and ER-beta, occur, each with distinct tissue and cell patterns of expression. Pelletier and El-Alfy (2000) studied the immunocytochemical localization of ESRA and ESRB in human reproductive tissues. In the ovary, ERB immunoreactivity was found in nuclei of granulosa cells of growing follicles at all stages from primary to mature follicles, interstitial gland, and germinal epithelium cells. Nuclear staining for ERA occurred in thecal, interstitial gland, and germinal epithelium cells. In the uterus, strong ERA immunoreactivity was detected in nuclei of epithelial, stromal, and muscle cells.Synonyms: ER alpha, ESR, ESR1, Estradiol receptor, NR3A1, Nuclear receptor subfamily 3 group A member 1

    基因ID

    2099

    途径

    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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