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Dystrophin 抗体
DMD
适用: 人, 小鼠, 大鼠, 小鸡
WB, IHC (p)
宿主: 小鼠
Monoclonal
DYS-48
unconjugated
Dystrophin抗体详情
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抗原
See all Dystrophin (DMD) 抗体
Dystrophin (DMD)
适用
All reactivities for Dystrophin 抗体
人, 小鼠, 大鼠, 小鸡
宿主
All hosts for Dystrophin 抗体
小鼠
克隆类型
All clonalities for Dystrophin 抗体
单克隆
标记
All conjugates for Dystrophin 抗体
This Dystrophin antibody is un-conjugated
应用范围
All applications for Dystrophin 抗体
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
特异性
This antibody reacts to Dystrophin.
纯化方法
Affinity chromatography
免疫原
Recombinant human dystrophin fragment.
克隆位点
DYS-48
亚型
IgG2b
Top Product
Discover our top product DMD Primary Antibody
Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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溶解方式
Restore with 1.2 % sodium acetate or neutral PBS
浓度
0,1 mg/mL
缓冲液
1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
-20 °C
储存方法
Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Dystrophin目标详情
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抗原
Dystrophin (DMD)
别名
Dystrophin / DMD (DMD 产品 )
别名
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背景
Dystrophin(DMD) gene has 79 exons spanning at least 2,300 kb (2.3 Mb). The C terminus of the dystrophin protein is encoded by a highly conserved, alternatively spliced region of the gene. beta-dystroglycan binding activity is expressed by the dystrophin fragment spanning amino acids 3026-3345 containing the ZZ domain. DMD transcript is formed by at least 60 exons, the first half of the transcript is formed by a minimum of 33 exons spanning nearly 1000 kb, and the remaining portion has at least 27 exons that may spread over a similar distance. Dystrophin gene is expressed at a higher level in primary cultures of neuronal cells than in astro-glial cells derived from adult mouse brain.over expression of dystrophin prevents the development of the abnormal mechanical properties associated with dystrophic muscle without causing deleterious side effects.
基因ID
1756
NCBI登录号
NP_000100
UniProt
P11532
途径
Skeletal Muscle Fiber Development
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