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Dystrophin 抗体

This anti-Dystrophin antibody is a 小鼠 单克隆 antibody detecting Dystrophin in WB 和 IHC (p). Suitable for 人, 小鼠, 大鼠 和 小鸡.
产品编号 ABIN1107040
发货至: 中国

Quick Overview for Dystrophin 抗体 (ABIN1107040)

抗原

See all Dystrophin (DMD) 抗体
Dystrophin (DMD)

适用

人, 小鼠, 大鼠, 小鸡

宿主

  • 47
  • 33
小鼠

克隆类型

  • 56
  • 24
单克隆

标记

  • 35
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
This Dystrophin antibody is un-conjugated

应用范围

  • 51
  • 27
  • 26
  • 15
  • 10
  • 8
  • 7
  • 6
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

DYS-48
  • 特异性

    This antibody reacts to Dystrophin.

    纯化方法

    Affinity chromatography

    免疫原

    Recombinant human dystrophin fragment.

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    Restore with 1.2 % sodium acetate or neutral PBS

    浓度

    0,1 mg/mL

    缓冲液

    1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Dystrophin (DMD)

    别名

    Dystrophin / DMD

    背景

    Dystrophin(DMD) gene has 79 exons spanning at least 2,300 kb (2.3 Mb). The C terminus of the dystrophin protein is encoded by a highly conserved, alternatively spliced region of the gene. beta-dystroglycan binding activity is expressed by the dystrophin fragment spanning amino acids 3026-3345 containing the ZZ domain. DMD transcript is formed by at least 60 exons, the first half of the transcript is formed by a minimum of 33 exons spanning nearly 1000 kb, and the remaining portion has at least 27 exons that may spread over a similar distance. Dystrophin gene is expressed at a higher level in primary cultures of neuronal cells than in astro-glial cells derived from adult mouse brain.over expression of dystrophin prevents the development of the abnormal mechanical properties associated with dystrophic muscle without causing deleterious side effects.

    基因ID

    1756

    NCBI登录号

    NP_000100

    UniProt

    P11532

    途径

    Skeletal Muscle Fiber Development
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