TdT 抗体 (C-Term)
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Quick Overview for TdT 抗体 (C-Term) (ABIN1107004)
抗原
See all TdT (DNTT) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects DNTT / TDT at C-term.
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交叉反应 （详细）
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Species reactivity (expected):Rat, mouse
Species reactivity (tested):Human -
纯化方法
- Immunogen affinity purified
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminal of human TDT .Remarks: Sequence is identical to the related rat and mouse sequence.
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亚型
- IgG
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anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 52-192) antibody
DNTT 适用: 人, 大鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4B10A6 unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 52-192) antibodyDNTT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B10C3 unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) antibodyDNTT 适用: 人 IHC 宿主: 兔 Monoclonal 453R unconjugated Recombinant Antibody
anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 1-110) antibodyDNTT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H5 unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 351-450) antibodyDNTT 适用: 人, 小鼠, 大鼠 ELISA, FACS, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 1-509) antibodyDNTT 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) antibodyDNTT 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB1660 unconjugated Recombinant Antibody
anti-Deoxynucleotidyltransferase, terminal (DNTT) (Internal Region) antibodyDNTT 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 316-509) antibodyDNTT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 260-509) antibodyDNTT 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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缓冲液
- 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
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别名
- DNTT / TDT
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背景
- Terminal Deoxynucleotidyl Transferase, also known as TdT and terminal transferase, is a unique DNA polymerase without template direction catalyzes the addition of deoxyribonucleotides onto the 3-prime-hydroxyl end of DNA primers.1 Its gene is mapped to the region 10q23-q24.2 And TDT Cdna contains an open reading frame of 1,530 basepairs corresponding to a protein containing 510 amino acids.3 TDT may be responsible for inserting nucleotides (N regions) at the V(H)-D and D-J(H) junctions of immunoglobulin genes. The enzyme is present in immature thymocytes, some bone marrow cells,transformed pre-B and pre-T cell lines, and leukemia cells. Additionally, TdT catalyses the addition of nucleotides to the 3' terminus of a DNA molecule. Unlike most DNA polymerases it does not require a template. The preferred substrate of this enzyme is a 3'-overhang, but it can also add nucleotides to blunt or recessed 3' ends. Cobalt is a necessary cofactor.Synonyms: DNA nucleotidylexotransferase, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, Terminal transferase
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基因ID
- 1791
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NCBI登录号
- NP_001017520
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UniProt
- P04053
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途径
- DNA Damage Repair
抗原
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