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Desmin 抗体

This anti-Desmin antibody is a 小鼠 单克隆 antibody detecting Desmin in WB, IF 和 IHC (fro). Suitable for 人, 大鼠, 小鼠, 小鸡, Hamster, Pig, 犬, 兔 和 斑马鱼.
产品编号 ABIN1106975
发货至: 中国

Quick Overview for Desmin 抗体 (ABIN1106975)

抗原

See all Desmin (DES) 抗体
Desmin (DES)

适用

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人, 大鼠, 小鼠, 小鸡, Hamster, Pig, 犬, 兔, 斑马鱼

宿主

  • 133
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小鼠

克隆类型

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单克隆

标记

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This Desmin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

RD301
  • 纯化方法

    Purified

    免疫原

    Cytoskeletal desmin extract of chicken gizzard.

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS with 0.09 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the lyophilized antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer. store the reconstituted antibody at -20 °C.
  • 抗原

    Desmin (DES)

    别名

    Desmin

    背景

    Desmin (53 kDa) exhibits a high degree of tissue specificity, its expression being predominantly confined to all types of muscle cells (cardiac, skeletal and smooth muscle). Regulation of desmin expression is stage and tissue-specific, since it is induced during terminal development of, for example, skeletal muscle cell differentiation. In skeletal en cardiac muscle cells desmin is localized in the Z-disk region and at the intercalated disk. The expression pattern of desmin in smooth muscle is much more heterogenous. Coexpression of vimentin and desmin has been observed in tumors derived from muscle tissue, i.e. rhabdomyosarcomas and leiomyosarcomas. Furthermore, during myocard dysfunction dramatic changes in the distribution of desmin have been observed.Synonyms: DES

    基因ID

    9031

    UniProt

    P02542
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