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DAXX 抗体

This anti-DAXX antibody is a 小鼠 单克隆 antibody detecting DAXX in WB, IF 和 EIA. Suitable for 人.
产品编号 ABIN1106953
发货至: 中国

Quick Overview for DAXX 抗体 (ABIN1106953)

抗原

See all DAXX 抗体
DAXX (Death-Domain Associated Protein (DAXX))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This DAXX antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

克隆位点

7A11
  • 特异性

    This antibody reacts to DAXX.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography on Protein G

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, 0,03 % sodium azide, 50 % glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    DAXX (Death-Domain Associated Protein (DAXX))

    别名

    DAXX

    背景

    DAXX (death-domain associated protein), it is a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.Synonyms: BING2, DAP6, Death domain-associated protein 6, EAP1, ETS1-associated protein 1, Fas death domain-associated protein

    分子量

    81 kDa

    基因ID

    1616

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway
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