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Cytokeratin 18 抗体

This anti-Cytokeratin 18 antibody is a 小鼠 单克隆 antibody detecting Cytokeratin 18 in WB, IF, FACS, IHC (p) 和 IHC (fro). Suitable for 人, 犬, Cat 和 斑马鱼.
产品编号 ABIN1106920
发货至: 中国

Quick Overview for Cytokeratin 18 抗体 (ABIN1106920)

抗原

See all Cytokeratin 18 (KRT18) 抗体
Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

适用

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人, 犬, Cat, 斑马鱼

宿主

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小鼠

克隆类型

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单克隆

标记

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This Cytokeratin 18 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

DE-K18
  • 特异性

    This antibody reacts exclusively with cytokeratin 18 which is present in glandular epithelial cells of the digestive, respiratory, and urogenital tracts, endocrine and exocrine cells and mesothelial cells, as well as adenocarcinomas originating from them.

    纯化方法

    Purified

    免疫原

    Cytoskeletal preparation extracted from the human vulvar squamous carcinoma cell line A431.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS with 0.09 % sodium azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store lyophilized (preferably in a desiccator) at 2-8 °C and reconstituted (in aliquots) at -20 °C.
  • 抗原

    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

    别名

    Cytokeratin 18

    背景

    Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.Synonyms: CK18, CYK18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, K18, KRT18, Keratin 18, Keratin type I cytoskeletal 18, Keratin-18

    基因ID

    3875

    NCBI登录号

    NP_000215

    UniProt

    P05783

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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