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COL2 抗体

COL2 适用: 人, 小鼠, 大鼠, 小鸡, Cow IHC (p), IHC (fro), Func, EIA 宿主: 小鼠 Monoclonal M2139 unconjugated
产品编号 ABIN1106744
发货至: 中国
  • 抗原 See all COL2 抗体
    COL2 (Collagen, Type II (COL2))
    适用
    • 44
    • 32
    • 28
    • 23
    • 18
    • 12
    • 10
    • 4
    • 1
    人, 小鼠, 大鼠, 小鸡, Cow
    宿主
    • 42
    • 12
    • 10
    • 4
    小鼠
    克隆类型
    • 56
    • 12
    单克隆
    标记
    • 34
    • 12
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COL2 antibody is un-conjugated
    应用范围
    • 51
    • 38
    • 22
    • 20
    • 15
    • 14
    • 13
    • 13
    • 9
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Enzyme Immunoassay (EIA)
    特异性
    The monoclonal antibody M2139 reacts with the J1 epitope (triple helical position 551-564) of collagen type II. It has been shown to induce CAIA in naive mice after injection of lipopolysacharide (LPS). However, in combination with the monoclonal antibody CIIC1 (cat.no. AM26375PU-N), binding to the C1 epitope of CII, the pair of monoclonal antibodies induce arthritis in different strains of mice without any other stimulants. The presence of secondary stimulus, LPS, increases the disease incidence and severity.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat, bovine, chicken
    纯化方法
    Protein G
    克隆位点
    M2139
    亚型
    IgG2b
    Top Product
    Discover our top product COL2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.1 % bovine serum albumin
    储存条件
    4 °C
    储存方法
    Store at 2 - 8 °C.
  • 抗原
    COL2 (Collagen, Type II (COL2))
    别名
    Collagen Type II (COL2 产品)
    别名
    PT antibody, RPRGL2 antibody, THPH1 antibody, Cf-2 antibody, Cf2 antibody, FII antibody, thrombin antibody, prothrombin antibody, CAP18 antibody, Cnlp antibody, Cramp antibody, FALL39 antibody, MCLP antibody, coagulation factor II, thrombin antibody, coagulation factor II antibody, cathelicidin antimicrobial peptide antibody, Cuticle collagen 2 antibody, collagen type II alpha 1 chain antibody, F2 antibody, Camp antibody, col-2 antibody, COL2A1 antibody
    背景
    Collagen is a structural protein in bone, cartillage and connective tissue. Collagen type II (CII) is the major collagen of the nucleus pulposa (a component of spine), cartilage and vitreous (a component of the eye). The most commonly used animal model for rheumatoid arthritis (RA) is the collagen-induced arthritis (CIA). Transfer of collagen type II specific monoclonal antibodies induces an acute form of arthritis (collagen type II antibody induced arthritis, CAIA).Synonyms: COL2, Collagen II
    基因ID
    1280
    NCBI登录号
    NP_001835
    UniProt
    P02458
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