CKB 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for CKB 抗体 (N-Term) (ABIN1106703)
抗原
See all CKB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- N-Term
-
序列
- SNSHNALKLR FPAEDEF
-
特异性
- The monoclonal antibody CK-BYK/21E10 recognizes creatine kinase B-type, also known as CKB.
-
交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat, rabbit
-
纯化方法
- Protein G
-
免疫原
- Synthetic 17-mer peptide corresponding to the N-terminal sequence of human creatine kinase brain-type
-
亚型
- IgG2b
-
-
anti-Creatine Kinase, Brain (CKB) antibody
KD Validated CKB 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 24GB4350 unconjugated Recombinant Antibody
anti-Creatine Kinase, Brain (CKB) antibodyKD Validated CKB 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 24GB4355 unconjugated Recombinant Antibody
anti-Creatine Kinase, Brain (CKB) antibodyCKB 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Creatine Kinase, Brain (CKB) (AA 11-367) antibodyCKB 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal D3 unconjugated
anti-Creatine Kinase, Brain (CKB) (AA 2-270) antibodyCKB 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Creatine Kinase, Brain (CKB) antibodyKD Validated CKB 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB7005 unconjugated
anti-Creatine Kinase, Brain (CKB) (AA 66-179) antibodyCKB 适用: 人, 小鼠 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Creatine Kinase, Brain (CKB) (AA 7-381) antibodyCKB 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Creatine Kinase, Brain (CKB) antibodyCKB 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Creatine Kinase, Brain (CKB) (AA 1-381) antibodyCKB 适用: 人 WB, ICC, ELISA, FACS, IF 宿主: 小鼠 Monoclonal AT8E4 unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 0.1 mg/mL
-
缓冲液
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Store at 2 - 8 °C.
-
-
- CKB (Creatine Kinase, Brain (CKB))
-
别名
- CKBB
-
背景
- Human CKB is a protein of 381 amino acids (~45 kDa), expressed in a number of tissues. CKB is most abundant in adult brain, approx. 5-fold lower in the stomach, 10-fold lower in the heart and barely detectable in liver. In brain, whereas most CKB has been shown to be cytosolic, several of the reactions requiring CKB are membrane-associated. CKB belongs to the creatine kinase (CK) isoenzymes that catalyse the synthesis of phosphocreatine (PCr) and its subsequent use in the regeneration of ATP in cell types where the consumption of ATP is rapid and/or sudden. In the brain the different CK isoforms constitute an energy shuttle wherein ATP produced in the mitochondria is used by a mitochondrial CK [e.g. ubiquitous mitochondrial creatine kinase (uMi-CK)] to generate PCr, which is then transported and used by a cytoplasmic CK [e.g. brain creatine kinase (CKB)] to regenerate ATP at discrete cellular sites of high ATP turnover. CKB appears to have a role in regenerating ATP needed for the transport of ions and neurotransmitters since CKB has been localized to brain synaptic plasma membranes, possibly coupled to Na+/K+-ATPase and acetylcholine receptor-rich membranes. Expression of CKB is developmentally controlled: in rat, brain CKB protein at birth is extremely low and increases 10-fold until week 4. This reflects the many energy-demanding processes in brain during brain development.Synonyms: B-CK, CKB, Creatine kinase B chain, Creatine kinase B-type, Creatine kinase BB
-
基因ID
- 1152
-
NCBI登录号
- NP_001814
-
UniProt
- P12277
抗原
-
