C5AR1 抗体
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Quick Overview for C5AR1 抗体 (ABIN1106597)
抗原
See all C5AR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody detects C5aR.
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Protein G
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
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有效期
- 6 months
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- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
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别名
- CD88 / C5R1
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背景
- The human anaphylatoxin C5a is a 74-residu glycopolypeptide which is generated by proteolytic cleavage of the complement factor C5 in the course of complement activation. A variety of biological effects evoked by C5a could be demonstrated, rendering this molecule an important mediator of inflammation, with granulocytes and macrophages as the main target cells. All cellular responses to C5a are specifically mediated by interactions with the membrane bound C5a receptor, a seven transmembrane GTP-binding-protein-coupled receptor that belongs to the rhodopsin supergene family. The C5a receptor is approximately 45 kDa.Synonyms: C5AR1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, Complement Component 5a Receptor 1
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基因ID
- 728
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NCBI登录号
- NP_001727
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UniProt
- P21730
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途径
- Complement System
抗原
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