P-Selectin 抗体 (PE)
Quick Overview for P-Selectin 抗体 (PE) (ABIN1106513)
抗原
See all P-Selectin (SELP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognises the CD62P cell surface antigen.
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Human platelet membrane glycoproteins.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Restore with 1 mL distilled water.
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缓冲液
- PBS, 0.09 % Sodium Azide, 1 % BSA, 5 % Sucrose
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Prior to and following reconstitution store the antibody at 2-8 °C.
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- P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
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别名
- CD62P / P-Selectin
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背景
- CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster. The antigen is expressed in the surface of activated platelets and also on endothelial cells both of blood and lymph vessels.Synonyms: CD62 antigen-like family member P, GMP-140, GMRP, GRMP, Granule membrane protein 140, LECAM3, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, SELP
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基因ID
- 6403
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NCBI登录号
- NP_002996
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UniProt
- P16109
抗原
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